DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp1 and ppid

DIOPT Version :9

Sequence 1:	NP_523366.2	Gene:	Cyp1 / 32595	FlyBaseID:	FBgn0004432	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001002065.1	Gene:	ppid / 415155	ZFINID:	ZDB-GENE-040625-34	Length:	371	Species:	Danio rerio

Alignment Length:	167	Identity:	100/167 - (59%)
Similarity:	121/167 - (72%)	Gaps:	8/167 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 PRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFG--------YKGSIFHRVIPNF 123
            ||||||:....|.:||:|.||.:|||||||||||||||||||.|        :||..|||:|.:|
Zfish    16 PRVFFDVEIGAERVGRVVFELFADVVPKTAENFRALCTGEKGVGKSTGKPLHFKGCPFHRIIKSF 80

  Fly   124 MCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNK 188
            |.|||||:|.|||||:||||:||.||||..||...|:|||||||.|||||||||.||.|..||.|
Zfish    81 MIQGGDFSNQNGTGGESIYGDKFEDENFHYKHDREGLLSMANAGPNTNGSQFFITTVPTPHLDGK 145

  Fly   189 HVVFGEVVEGLDVVKKIESYGSQSGKTSKKIIVANSG 225
            |||||:|::|:.|||.:|:..::.....|..::|..|
Zfish   146 HVVFGQVLKGMGVVKMLEAMETKEDNPVKPCVIAECG 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp1	NP_523366.2	cyclophilin_ABH_like	67..225	CDD:238907	99/165 (60%)
ppid	NP_001002065.1	cyclophilin_ABH_like	16..182	CDD:238907	99/165 (60%)
		TPR_11	223..304	CDD:290150
		TPR repeat	223..268	CDD:276809
		TPR_12	271..340	CDD:290160
		TPR repeat	273..303	CDD:276809
		TPR repeat	308..336	CDD:276809
		TPR_1	309..341	CDD:278916
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820