DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp1 and ppib

DIOPT Version :9

Sequence 1:	NP_523366.2	Gene:	Cyp1 / 32595	FlyBaseID:	FBgn0004432	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_998184.1	Gene:	ppib / 406292	ZFINID:	ZDB-GENE-040426-1955	Length:	216	Species:	Danio rerio

Alignment Length:	228	Identity:	111/228 - (48%)
Similarity:	143/228 - (62%)	Gaps:	24/228 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVSFCATLIRQFRHRSAAAFQIAESAILANKSITLASSACSVNRGQLQFGIQIVREYSKASKMST 65
            ||..|...::         |.:|.:.|:.:....|..|....:            |..|..|::.
Zfish     1 MVRICERRMK---------FLVAVTLIVGSVVFLLFPSETEAD------------EKKKGPKVTA 44

  Fly    66 LPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDF 130
              :|:||:...:|..||||:.|....||||.|||..|.|||||||||||.|||||.:||.|||||
Zfish    45 --KVYFDIKIGDEDAGRIVIGLFGKTVPKTTENFLQLATGEKGFGYKGSKFHRVIKDFMIQGGDF 107

  Fly   131 TNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEV 195
            |..:|||||||||::||||||:|||.|.|.|||||||.:||||||||.||:|.|||.||||||::
Zfish   108 TRGDGTGGKSIYGDRFPDENFKLKHYGPGWLSMANAGKDTNGSQFFITTVQTPWLDGKHVVFGKI 172

  Fly   196 VEGLDVVKKIESYGSQS-GKTSKKIIVANSGSL 227
            :||:|||:|||:..:.. .|..|.:.:.:||.:
Zfish   173 LEGMDVVRKIEATKTDGRDKPLKDVSIHDSGKI 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp1	NP_523366.2	cyclophilin_ABH_like	67..225	CDD:238907	98/158 (62%)
ppib	NP_998184.1	cyclophilin_ABH_like	45..203	CDD:238907	98/157 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53630
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830