DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp1 and cyn-13

DIOPT Version :9

Sequence 1:	NP_523366.2	Gene:	Cyp1 / 32595	FlyBaseID:	FBgn0004432	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001255925.1	Gene:	cyn-13 / 178487	WormBaseID:	WBGene00000889	Length:	331	Species:	Caenorhabditis elegans

Alignment Length:	170	Identity:	107/170 - (62%)
Similarity:	130/170 - (76%)	Gaps:	0/170 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 SKASKMSTLPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPN 122
            |.:|..:.||||:..:......:||||:|||:||.||||||||.|||||:||||:||||||:||.
Worm   130 SSSSASTKLPRVYLGVKIGIRYIGRIVIELRTDVTPKTAENFRCLCTGERGFGYEGSIFHRIIPK 194

  Fly   123 FMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDN 187
            ||.||||||..:|||||||||.||.||||.|:||..|.:||||.|||||||||||||.||.|||.
Worm   195 FMLQGGDFTKGDGTGGKSIYGTKFDDENFTLRHTMPGTVSMANCGANTNGSQFFICTEKTDWLDG 259

  Fly   188 KHVVFGEVVEGLDVVKKIESYGSQSGKTSKKIIVANSGSL 227
            ||||||.||||:::|:::|..|:.|||....:.:..||.:
Worm   260 KHVVFGHVVEGMNIVRQVEQQGTPSGKPQMVVKIVESGEI 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp1	NP_523366.2	cyclophilin_ABH_like	67..225	CDD:238907	102/157 (65%)
cyn-13	NP_001255925.1	RRM	<10..>115	CDD:223796
		RRM_PPIE	13..85	CDD:240793
		cyclophilin_ABH_like	139..297	CDD:238907	102/157 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D563773at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920