DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cyp1 and PPIH

DIOPT Version :9

Sequence 1:NP_523366.2 Gene:Cyp1 / 32595 FlyBaseID:FBgn0004432 Length:227 Species:Drosophila melanogaster
Sequence 2:NP_006338.1 Gene:PPIH / 10465 HGNCID:14651 Length:177 Species:Homo sapiens


Alignment Length:167 Identity:87/167 - (52%)
Similarity:116/167 - (69%) Gaps:6/167 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly    67 PRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGE-----KGFGYKGSIFHRVIPNFMCQ 126
            |.||||::...:.:||:.:||.:|||||||||||..||||     ...|||||.|||||.:||.|
Human    11 PVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQ 75

  Fly   127 GGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVV 191
            ||||.|.:|||..|||...|.||||:|:|:..|:|||||:|.:|||.||||...|..|||.||||
Human    76 GGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVV 140

  Fly   192 FGEVVEGLDVVKKIESYGS-QSGKTSKKIIVANSGSL 227
            ||::::||.|::|||:..: .:.|....::::..|.:
Human   141 FGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM 177

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp1NP_523366.2 cyclophilin_ABH_like 67..225 CDD:238907 86/163 (53%)
PPIHNP_006338.1 cyclophilin 8..177 CDD:412213 87/165 (53%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0652
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1403619at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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