DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Had1 and hadh

DIOPT Version :9

Sequence 1:NP_001285320.1 Gene:Had1 / 32592 FlyBaseID:FBgn0286508 Length:315 Species:Drosophila melanogaster
Sequence 2:NP_001003515.1 Gene:hadh / 445121 ZFINID:ZDB-GENE-040801-261 Length:309 Species:Danio rerio


Alignment Length:307 Identity:84/307 - (27%)
Similarity:136/307 - (44%) Gaps:57/307 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 VGIVGSGLIGRSWSMLFASVGYQVVLYDILPEQVSTALTATQKELQDLEAKGLLRG-KLTAAQQF 71
            |.::|.||:|...:.:.||.|:.|||.|            |..::.:..|||:... |..|.::|
Zfish    25 VTVIGGGLMGAGIAQVAASTGHSVVLVD------------TSADILNKSAKGIENSLKRVAKKKF 77

  Fly    72 A---------------CISGTNDLKELVKGAIFVQECIPERLDLKKALYKQLDAVVGPNTILSSS 121
            |               .:|.:.|...:|.|...|.|.|.|.|.:|:.|:..||.|...:||.:|:
Zfish    78 AEKPEDGEAFVQKVLKNVSTSTDAASVVHGTDLVVEAIVENLKVKQDLFGALDKVAPEHTIFASN 142

  Fly   122 TSTFLPSLFSADLKNKANVLVS----HPVNPPYYVPLVEIVPAPWTKPEWVKKTRALMEEIGQKP 182
            ||    ||..||:.:....|..    |..||...:.|||::..|.|..:.........:.:|:.|
Zfish   143 TS----SLPIADIASCTARLDRFGGLHFFNPVPMMKLVEVIKTPATSQQTFDALLEFSKALGKHP 203

  Fly   183 VTLSREIEGFALNRIQYAILNETWRLVEAGILNVKDIDSVMSNGLGPRYAFLGP--------LET 239
            |: .::..||.:||:....:.|..||.|.|..:.:|||..|..|.|  |. :||        |:|
Zfish   204 VS-CKDTPGFIVNRLLVPYMLEAVRLHERGHGSKEDIDVAMKLGAG--YP-MGPFELLDYVGLDT 264

  Fly   240 AHLNAEGMANYFERYSNTIYAVSETMGPTPKMEGPVAV-EVAKQLGE 285
            :....:|.  :.:...|.::|      |:|.:...|:. ::.|:.||
Zfish   265 SKFIIDGW--HAKDPDNPLFA------PSPLLNKLVSEGKLGKKTGE 303

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Had1NP_001285320.1 PRK06129 7..310 CDD:235706 84/307 (27%)
3HCDH_N 7..183 CDD:280833 53/194 (27%)
3HCDH 191..>265 CDD:279114 23/81 (28%)
hadhNP_001003515.1 FadB 20..307 CDD:224170 84/307 (27%)
3HCDH_N 24..209 CDD:280833 55/200 (28%)
3HCDH 211..308 CDD:279114 29/104 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1250
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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