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Protein Alignment CG3632 and MTMR7

DIOPT Version :9

Sequence 1:	NP_001096996.1	Gene:	CG3632 / 32589	FlyBaseID:	FBgn0030735	Length:	1250	Species:	Drosophila melanogaster
Sequence 2:	NP_004677.3	Gene:	MTMR7 / 9108	HGNCID:	7454	Length:	660	Species:	Homo sapiens

Alignment Length:	700	Identity:	188/700 - (26%)
Similarity:	303/700 - (43%)	Gaps:	148/700 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 LIVNCKDASTVRCSFPSAEQCSDWQRRIHLMIGVPESLETLFAFPFYSWTCDVLGSGNGSGIVSA 163
            |::.||:...::...|....|.|....: :.:..|...|.|:.|.|
Human    70 LLIRCKNFQIIQLIIPQERDCHDVYISL-IRLARPVKYEELYCFSF------------------- 114

  Fly   164 QANGNGLIAKDRCLTLHNGLAKPTANVTASNPLPDPASETISAAMSNRLQRSVRYESDFKNEVAR 228
                                          ||:.|         ...|.|..|..  |...|..|
Human   115 ------------------------------NPMLD---------KEEREQGWVLI--DLSEEYTR 138

  Fly   229 LGFDLKGSWRISTANADFKLCPSYPPKLLVPCCITDEMLHNVANFRGSRRLPAVVWRHQKSGAIL 293
            :|.. ...|::|..|.|:::|.|||.:|.||...|..::...:.||..||.|.:.:.::.:.|.:
Human   139 MGLP-NHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASI 202

  Fly   294 ARCSQPEVGWLGWRNTRDEQLLKALADACAFDRGEHARHSTCANAKAQPTKGSKETNGQSGLSGK 358
            .|.|||..|:.. |...|||:|:|:.                                      |
Human   203 CRSSQPLSGFSA-RCLEDEQMLQAIR--------------------------------------K 228

  Fly   359 SSPSLDDSSHEELTLDEIKKILIVDARSYTSAVTNRARGGGCECIEYYPCAEIEFMNLGNIHAIR 423
            ::|..|             .:.:||.|...:|:.|||.|.|.|..:.|...:.:|:.:.|||.:|
Human   229 ANPGSD-------------FVYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMR 280

  Fly   424 KSFHAVRQLC-ASSPDDPNWYGQLEKTMWMQHLSGLLGATMTVVHTIEKNGRPVLVHCSDGWDRT 487
            .|...:.::| ..||...::...||.:.|::|:..::.|.:.:...:.:.|..||||||||||||
Human   281 NSLQKMLEVCELKSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRT 345

  Fly   488 PQIVATAQLCLDPYYRTVEGFRVLVEREWLNFGHKFADRSGNGPNSDEVNERCPVFLQWLDLVHQ 552
            .|:.:.|.|.|||:|||::||.||:|::|::|||||..|.||  ...:..|..||..|:::.|.|
Human   346 AQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGN--LDGDPKEISPVIDQFIECVWQ 408

  Fly   553 IHRQYPCSFEFSISYLIKLAQHSLSCLFGTFLCNSLRERIENSVFDRTFSVWPFLAETM--YRNP 615
            :..|:||:|||:..:||.:..|..||.||.|||||.:||.|..:.:||:|:|..|.:..  |.||
Human   409 LMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNP 473

  Fly   616 LYK---HETEKVL-WPAHSVRFLY-FWSDVY----LGSLGNKNGTD-LPLLSNERQSGHNGLMAK 670
            |::   .:|:..| .|.....|:| |||.:|    .|....::.|| |..:..|.|.....|.|.
Human   474 LFRADHSQTQGTLHLPTTPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEAL 538

  Fly   671 TRSSEDLTTNELGQSTISRRSSDPN-----LTVESIVTDC---FNANSNSMFDIRSEANNS---- 723
            ....|.:...:|..:.:..:.|:|:     .|.::.:.:.   ::.|..| |..||.:...
Human   539 EERLEKIQKVQLNCTKVKSKQSEPSKHSGFSTSDNSIANTPQDYSGNMKS-FPSRSPSQGDEDSA 602

  Fly   724 ---VSENVQESVKD---SKEVELDVTDATEVGPCGRSNNPIPDFHNDQST 767
               ..:|::.|..|   :.:.|..|.|.:...|.|..:.|..|...|:.:
Human   603 LILTQDNLKSSDPDLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDS 652

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.