| Sequence 1: | NP_001096996.1 | Gene: | CG3632 / 32589 | FlyBaseID: | FBgn0030735 | Length: | 1250 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001373268.1 | Gene: | SBF2 / 81846 | HGNCID: | 2135 | Length: | 1881 | Species: | Homo sapiens |
| Alignment Length: | 1096 | Identity: | 268/1096 - (24%) |
|---|---|---|---|
| Similarity: | 418/1096 - (38%) | Gaps: | 283/1096 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 DFMVPIHTMSDGSPPPSI----CFIRAAESYPKSQMEKEDSQLFVPFQELAGESIKYL----GRT 58
Fly 59 D--------------DGILALSNYRIFL----SKQSTGYETYV---PLGLI-------------- 88
Fly 89 ---ESVQVRDL-FQLIVNCKDASTVRCSFPSAEQCSDWQRRIHLMIGVPESLETLFAFPFYSWTC 149
Fly 150 DVL-----------GSGNGSGIVSAQANGNGLIAKDRCLTLHNG------LAKPTAN----VTAS 193
Fly 194 NPLPDPASETISAAMSNRLQRSVRYESDFKNEVARLGF-DLKGS--------WRISTANADFKLC 249
Fly 250 PSYPPKLLVPCCITDEMLHNVANFRGSRRLPAVVWRHQKSGAILARC----SQPEVGWLGWRNT- 309
Fly 310 --------------RDEQLLKALADAC------------------AFDRGEHARHSTCANAKAQP 342
Fly 343 TKGSKETN-----GQSG------------------------LSGKS-SPSLDDSSHEELTLDEIK 377
Fly 378 KILIVDARSYTSAVTNRARGGGCE----CIEYYPCAEIEFMNLGNIHAIRKSFHAVRQLCASSP- 437
Fly 438 ------------DDPNWYGQLEKTMWMQHLSGLLGATMTVVHTIEKNGRPVLVHCSDGWDRTPQI 490
Fly 491 VATAQLCLDPYYRTVEGFRVLVEREWLNFGHKFADRS-------GNGPNSDEVNERCPVFLQWLD 548
Fly 549 LVHQIHRQYPCSFEFSISYLIKLAQHSLSCLFGTFLCNSLRERIEN-SVFD--------RTFSVW 604
Fly 605 PFLAETMYRNP-----LYKHETEKVLWPAHSVRFLYFWSDVYL-GSLGNKNGTDLPLLSNERQSG 663
Fly 664 HNGLMAKTRSSEDL-TTNELGQSTISRRS-----SDPNLTVESIVTDCFNANSNSMFDIRSEANN 722
Fly 723 SVSENVQESVKDSKEVELDVTDATEVGPCGRSNNP------IPDFHNDQSTASKRDILEVESQT- 780
Fly 781 --QRRSSLESSQLI---PGSVFIFGSSENDKNAVPSESEESLATSQKLNSESGRP-FFIFGSSEN 839
Fly 840 DQSPVPLKSEDTSDISRALWHGAIE-TSTDTLIPAEP---VQKPNSDNSSRDHITS 891 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG3632 | NP_001096996.1 | PH-like | 35..147 | CDD:302622 | 33/154 (21%) |
| Myotub-related | 221..590 | CDD:284109 | 138/468 (29%) | ||
| FYVE_MTMR4 | 1162..1221 | CDD:277272 | |||
| SBF2 | NP_001373268.1 | uDENN | 1..86 | CDD:214824 | |
| DENN | 116..298 | CDD:396629 | |||
| dDENN | 352..420 | CDD:129037 | |||
| SBF2 | 531..754 | CDD:403522 | |||
| PH-GRAM_MTMR13 | 882..1000 | CDD:275416 | 26/123 (21%) | ||
| PTP-MTMR13 | 1138..1517 | CDD:350437 | 116/409 (28%) | ||
| Required for homodimerization and interaction with MTMR2. /evidence=ECO:0000250|UniProtKB:E9PXF8, ECO:0000269|PubMed:15998640 | 1661..1714 | 11/58 (19%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1706..1726 | 3/19 (16%) | |||
| PH_Sbf1_hMTMR5 | 1774..1879 | CDD:269941 | 22/91 (24%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165155561 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG4471 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.740 | |||||