Protein Alignment CG3632 and Sbf2

DIOPT Version :9

• Sequence 1: NP_001096996.1
• Gene: CG3632 / 32589
• FlyBaseID: FBgn0030735
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: XP_006507990.1
• Gene: Sbf2 / 319934
• MGIID: 1921831
• Length: 1904
• Species: Mus musculus
• Alignment Length: 1130
• Identity: 243/1130 - (21%)
• Similarity: 383/1130 - (33%)
• Gaps: 407/1130 - (36%)

  Fly    23 RAAESYPKSQMEKEDSQLFVPFQELAGESIKYL----GRTD--------------DGILALSNYR 69
            |.:...|..|..|......:|.:|:..|.::.|    ||.:              :|.|.|:.||
Mouse   858 RESRRLPPIQKPKILRPALLPGEEIVCEGLRVLLDPDGREEATGGLLGGPQLLPAEGALFLTTYR 922

  Fly    70 IFL----SKQSTGYETYV---PLGLI-----------------ESVQVRDL-FQLIVNCKDASTV 109
            |..    ..|..|.:|.|   |:..|                 |.:|:... ||||....|...
Mouse   923 ILFRGTPHDQLVGEQTVVRSFPIASITKEKKITMQNQLQQSVQEGLQITSASFQLIKVAFDEEV- 986

  Fly   110 RCSFPSAEQCSDWQRRIHLMIGVPESLETLFAF-------------------PFYSWTCDVLGSG 155
                 |.|....::::: :....|:|:.:.|||                   .|.:::..::...
Mouse   987 -----SPEVVDIFKKQL-MKFRYPQSIFSTFAFAAGQTTPQIILPKQKEKNTSFRTFSKTIVKGA 1045

  Fly   156 NGSGIVSAQANGNGLIAKDRCLTL-HNGLAKPTAN----VTASNPLPDPASETISAAMSNRLQRS 215
            ..:|.::.   |...:.|.|..|: ...:.:|..|    ::.|:....|.|.|:.|:..:.:::.
Mouse  1046 KKAGKMTI---GRQYLLKKRTGTIVEERVNRPGWNEEDDISVSDDSELPTSTTLKASEKSTMEQL 1107

  Fly   216 VRYESDFKNEVARLGF-DLKGS--------WRISTANADFKLCPSYPPKLLVPCCITDEMLHNVA 271
            |  |.....:..|||. .:.|:        :|::.:|..:.||.|||..|::|..:.|..|..||
Mouse  1108 V--EKACFRDYQRLGLGTISGNSSRSKPEYFRVTASNRLYSLCRSYPGLLVIPQAVQDSSLPRVA 1170

  Fly   272 NFRGSRRLPAVVWRHQKSGAILARC----SQPEVGWLGWRNT---------------RDEQLLKA 317
            ......|||.|.|::.:||.:|.|.    .:..||....:|:               ..|:.|:|
Mouse  1171 RCYRHNRLPVVCWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAVSTSSLESSSSIEQEKYLQA 1235

  Fly   318 LADAC-------------------------------------------------AFDRGEHARHS 333
            |..|.                                                 :|.||.|. :.
Mouse  1236 LLTAVIVHQKLRGSSTLTVRPALALSPGTERRSSRMSTVLKQVVPGHLDVNPSNSFARGVHG-YR 1299

  Fly   334 TCANAKAQPTKGSKETNGQSG------------------------LSGKS-SPSLDDSSHEELTL 373
            ..:..::.|...:||.....|                        |:||. |.|..:|::.:
Mouse  1300 DKSFTQSNPKSSAKEPVHNQGVWASLRSSTRLISSPTSFIDVGARLAGKDHSASFSNSTYLQ--- 1361

  Fly   374 DEIKKILIVDARSYTSAVTNRARGGGCE----CIEYYPCAEIEFMNLGNIHAIRKSFHAVRQLCA 434
               .::|...|..|.....::.|....|    | |:.|   :||   ..|..::.||..:.:.|.
Mouse  1362 ---NQLLKRQAALYIFGEKSQLRSSKVEFAFNC-EFVP---VEF---HEIRQVKASFKKLMRACI 1416

  Fly   435 SSP-------------DDPNWYGQLEKTMWMQHLSGLLGATMTVVHTIEKNGRPVLVHCSDGWDR 486
            .|.             .|..|:.||.:.|.:          ..||..:.:||..|.|...:|||.
Mouse  1417 PSTIPTDSEVTFLKALGDSEWFPQLHRIMQL----------AVVVSEVLENGSSVWVCLEEGWDI 1471

  Fly   487 TPQIVATAQLCLDPYYRTVEGFRVLVEREWLNFGHKFADRSGNGPNSDEVNERCPVFLQWLDLVH 551
            |.|:.:.|||..||:|||:.|||.|||:|||:|||||:.||....|| :.....|:|||:||.||
Mouse  1472 TTQVTSLAQLLSDPFYRTIAGFRTLVEKEWLSFGHKFSQRSSLALNS-QGGGFAPIFLQFLDCVH 1535

  Fly   552 QIHRQYPCSFEFSISYLIKLAQHSLSCLFGTFLCNSLRERIEN-SVFD--------RTFSVWPFL 607
            |:|.|||..|||::.||..||.|.:|..|.|||.:|..||:|: ::||        :...:|..:
Mouse  1536 QVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGDKHAKKGVCIWECI 1600

  Fly   608 AETMYRNPLYKHETEKVLWPAHSVRFLYFWSDVYLGSLGNKNGTDLPLLSNERQSGHNGLMAKTR 672
            .:...|:|::               |.|.:|.|.:.:|
Mouse  1601 DKMHTRSPIF---------------FNYLYSPVEVEAL--------------------------- 1623

  Fly   673 SSEDLTTNELGQSTISRRSSDPNLTVESIVTDCFNANSNSMFDIRSEANNSVSENVQESVKDSKE 737
                                .||:.|.|:          ..:|..:|...|...:....:...|.
Mouse  1624 --------------------KPNVNVSSL----------KKWDYYTEETLSAGPSYDWMMLTPKH 1658

  Fly   738 VELDVTD-ATEVGPCGRSNNPIPDFHNDQSTASKRDILEVESQTQRRSSLESSQLIPGSVFIFGS 801
            ...:.:| |...||..:.....|.:  |..|.|:.|.|     |:..|.:|..:
Mouse  1659 FPYEESDVAGGAGPQSQRKTVWPCY--DDVTCSQPDAL-----TRLFSEIEKLE----------- 1705

  Fly   802 SENDKNAVPSESEESLATSQKLNSESGRPFFIFGSSENDQSPVPLKSEDTSDISRALWHGAIETS 866
                               .|||....|                             ||...|..
Mouse  1706 -------------------HKLNQTPER-----------------------------WHQLWEKV 1722

  Fly   867 TDTLIPAEPVQKPNSDNSSRDHITSPTMELVSGDRKLESTSTVQASKISQSYNNLPKVHIRPNAV 931
            |..|     .::|.:.:|.|....||.:                ||....||...|.:|
Mouse  1723 TTDL-----KEEPRTAHSLRHSAGSPGI----------------ASTNVPSYQKRPALH------ 1760

  Fly   932 ICPQRVDAFPHHLDLQVPRETTGNP 956
                     |.|..|...:.||..|
Mouse  1761 ---------PLHRGLGEDQSTTTAP 1776

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3632	NP_001096996.1	PH-like	35..147	CDD:302622	34/173 (20%)
		Myotub-related	221..590	CDD:284109	132/487 (27%)
		FYVE_MTMR4	1162..1221	CDD:277272
Sbf2	XP_006507990.1	uDENN	1..87	CDD:214824
		DENN	116..298	CDD:366936
		dDENN	352..420	CDD:129037
		SBF2	531..752	CDD:372054
		PH-GRAM_MTMR13	880..998	CDD:275416	26/123 (21%)
		PTP_DSP_cys	1136..1540	CDD:391942	111/428 (26%)
		PH_Sbf1_hMTMR5	1797..1902	CDD:269941

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846012
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830