Protein Alignment CG3632 and Mtmr2

DIOPT Version :10

• Sequence 1: NP_001096996.1
• Gene: CG3632 / 32589
• FlyBaseID: FBgn0030735
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: NP_001101593.1
• Gene: Mtmr2 / 315422
• RGDID: 1311865
• Length: 643
• Species: Rattus norvegicus
• Alignment Length: 725
• Identity: 217/725 - (29%)
• Similarity: 327/725 - (45%)
• Gaps: 161/725 - (22%)

  Fly     7 IHTMSDGSPPPSICFIRAAESYPKSQMEKEDSQLFVPFQELAGESIKYLGR----------TDDG 61
            |.|.:|.. .|.:..:|.|...    .|.|:..|      |.||:||.:.:          ...|
  Rat    50 ISTSADNF-SPDLRVLREANKL----AEMEEPAL------LPGENIKDMAKDVTYICPFTGAVRG 103

  Fly    62 ILALSNYRIFLS--KQSTGYETYVPLGLIESVQV--------RDLFQLIVNCKDASTVRCSFPSA 116
            .|.::|||::..  ::...:.....||:|..|:.        .:.:.|...|||...:|    .|
  Rat   104 TLTVTNYRLYFKSMERDPPFVLDASLGVISRVEKIGGASSRGENSYGLETVCKDIRNLR----FA 164

  Fly   117 EQCSDWQRRIHLMIGVPESLETLFAFPFYSWTCDVLGSGNGSGIVSAQANGNGLIAKD-RCLTLH 180
            .:.....||     .:.|:| ..:|||.                    :||..|.|.: :.:...
  Rat   165 HKPEGRTRR-----SIFENL-MKYAFPV--------------------SNGLPLFAFEYKEVFPE 203

  Fly   181 NGLAKPTANVTASNPLPDPASETISAAMSNRLQRSVRYESDFKNEVARLGFDLKGSWRISTANAD 245
            ||.           .|.||..|.....:.|.                        ||||:..|..
  Rat   204 NGW-----------KLYDPLLEYRRQGIPNE------------------------SWRITKVNER 233

  Fly   246 FKLCPSYPPKLLVPCCITDEMLHNVANFRGSRRLPAVVWRHQKSGAILARCSQPEVGWLGWRNTR 310
            ::||.:||..|.||..|.||.|..||:||...|:|.:.|.|.:|.|.:.|||||.||..|.|:..
  Rat   234 YELCDTYPALLAVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATVTRCSQPMVGVSGKRSKE 298

  Fly   311 DEQLLKALADACAFDRGEHARHSTCANAKAQPTKGSKETNGQSGLSGKSSPSLDDSSHEELTLDE 375
            ||:.|:|:.|                            :|.||
  Rat   299 DEKYLQAIMD----------------------------SNAQS---------------------- 313

  Fly   376 IKKILIVDARSYTSAVTNRARGGGCECIEYYPCAEIEFMNLGNIHAIRKSFHAVRQLCASSPDDP 440
             .||.|.|||...:||.|:|:|||.|..:.|..||:.|:::.|||.:|:|...::::...:.::.
  Rat   314 -HKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEET 377

  Fly   441 NWYGQLEKTMWMQHLSGLLGATMTVVHTIEKNGRPVLVHCSDGWDRTPQIVATAQLCLDPYYRTV 505
            :|...||.|.|::|:..:|...:.:...:|.....|:||||||||||.|:.:.|.|.||.||||:
  Rat   378 HWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTI 442

  Fly   506 EGFRVLVEREWLNFGHKFADRSGNGPNSDEVNERCPVFLQWLDLVHQIHRQYPCSFEFSISYLIK 570
            .||.||||:|||:|||:|..|.|:|..:....:|.|||||::|.|.|:.||:|.:|||:..:||.
  Rat   443 RGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLIT 507

  Fly   571 LAQHSLSCLFGTFLCNSLRERIENSVFDRTFSVWPFLAETM--YRNPLYKHETEKVLWPAHSVRF 633
            :..|..|||||||||||.::|.:.::..:|.|:|.::...:  :.|||:...:..||:|..|:|.
  Rat   508 ILDHLYSCLFGTFLCNSEQQRGKENLPKKTVSLWSYINSQLEDFTNPLFGSYSNHVLYPVASMRH 572

  Fly   634 LYFWSDVYLGSLGNKNGTDLPLLSNERQSGHNGLMAK----TRSSEDLTTNELGQST-ISRRSSD 693
            |..|...|: ....:.....|:.|..::     |:||    .|..|:|......:|| .|.|:|.
  Rat   573 LELWVGYYI-RWNPRMKPQEPIHSRYKE-----LLAKRTELQRKVEELQREISNRSTSSSERASS 631

  Fly   694 PNLTVESIVT 703
            |...|..:.|
  Rat   632 PAQCVTPVQT 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3632	NP_001096996.1	PH-like	35..147	CDD:473070	29/131 (22%)
		Myotub-related	221..591	CDD:461958	139/369 (38%)
		FYVE_MTMR4	1162..1221	CDD:277272
Mtmr2	NP_001101593.1	PH-like	73..187	CDD:473070	29/149 (19%)
		Myotub-related	202..528	CDD:461958	146/411 (36%)