Protein Alignment CG3632 and Mtmr6

DIOPT Version :10

• Sequence 1: NP_001096996.1
• Gene: CG3632 / 32589
• FlyBaseID: FBgn0030735
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: NP_001388129.1
• Gene: Mtmr6 / 219135
• MGIID: 2145637
• Length: 655
• Species: Mus musculus
• Alignment Length: 727
• Identity: 202/727 - (27%)
• Similarity: 324/727 - (44%)
• Gaps: 131/727 - (18%)

  Fly    50 ESIKYLGR--TDD----GILAL-SNYRIFLSKQSTGYETYVPLGLIESVQVRDL----FQLIVNC 103
            |.:|.|.|  |::    |.|.| :.:.:|:..|..  ||::....|.||:...|    ..|::.|
Mouse    10 EQVKLLDRFSTNNKSLTGTLYLTATHLLFIDAQQK--ETWILHHHIASVEKLALTTSGCPLVIQC 72

  Fly   104 KDASTVRCSFPSAEQCSDWQRRIHLMIGVPESLETLFAFPFYSWTCDVLGSGNGSGIVSAQANGN 168
            |:...|....|....|.|....: |.:......|.|:||.:           |.....:.:.||.
Mouse    73 KNFRIVHFIVPRERDCHDIYNSL-LQLSKQAKYEDLYAFSY-----------NPKQNDTERRNGW 125

  Fly   169 GLIAKDRCLTLHNGLAKPTANVTASNPLPDPASETISAAMSNRLQRSVRYESDFKNEVARLGFDL 233
            .||                                                 |...|..|:|..
Mouse   126 QLI-------------------------------------------------DLAAEYERMGVP- 140

  Fly   234 KGSWRISTANADFKLCPSYPPKLLVPCCITDEMLHNVANFRGSRRLPAVVWRHQKSGAILARCSQ 298
            ..:|::|.||.::|:|.:||.:|.||...:..::...:|||...|||.:.:..|.:.|.:.||||
Mouse   141 NANWQLSDANREYKVCETYPRELYVPRTASRPVIVGSSNFRSKGRLPVLSYCRQGTEAAICRCSQ 205

  Fly   299 PEVGWLGWRNTRDEQLLKALADACAFDRGEHARHSTCANAKAQPTKGSKETNGQSGLSGKSSPSL 363
            |..|:.. |...||.||:|::.|...:|..:. ..|....:.|....:::..|:. :...||...
Mouse   206 PLSGFSA-RCLEDEHLLQAISKANPGNRYMYV-VDTRPKHRMQSWWDTQKDIGRI-IVRISSKIW 267

  Fly   364 DDSSHEELTLDEIKKILIVDARSYTSAVTNRARGGGCECIEYYPCAEIEFMNLGNIHAIRKSFHA 428
            :|           :||...|.|...:|:.|||.|.|.|..:.|.....:|:.:.|||.:|.|...
Mouse   268 ND-----------EKIRESDERKRLNAIANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQK 321

  Fly   429 VRQLCASSPDDPN-WYGQLEKTMWMQHLSGLLGATMTVVHTIEKNGRPVLVHCSDGWDRTPQIVA 492
            :.::..|.....| :|..||.:.|::|:..:|.|.:.:...|......||||||||||||.|:.:
Mouse   322 LLEVNGSKGLSVNDFYSGLESSGWLRHIKAVLDAAIFLAKAIVVENASVLVHCSDGWDRTSQVCS 386

  Fly   493 TAQLCLDPYYRTVEGFRVLVEREWLNFGHKFADRSGNGPNSDEVNERCPVFLQWLDLVHQIHRQY 557
            ...|.||.||||::||.||:|::|::|||||::|.|:  ...:..|..|||.|:|:.|..:.:|:
Mouse   387 LGSLLLDSYYRTMKGFMVLIEKDWISFGHKFSERCGH--LDGDPREVSPVFTQFLECVWHLTQQF 449

  Fly   558 PCSFEFSISYLIKLAQHSLSCLFGTFLCNSLRERIENSVFDRTFSVWPFLAE--TMYRNPLYKHE 620
            |.:|||:.::|:::.:|..||.||.||.|..:||.|..:.::|:|:||||.:  ..|.||||..:
Mouse   450 PQAFEFNEAFLLQIHEHIHSCQFGNFLGNCQKEREELRLKEKTYSLWPFLLDDKKKYLNPLYSSK 514

  Fly   621 TEK--VLWPAHSVRFLYFWSDVY-------------LGSLGNKNGTDLPLLSNERQSGHNGLMAK 670
            :::  ||.|..:.....||.::|             |..:.|.|..     |.:.:.....|.||
Mouse   515 SQRLTVLEPNTASFNFKFWRNMYHQFDRTLHPRQSVLSIIMNMNEQ-----SKQLEEDIKDLEAK 574

  Fly   671 TRSSED-LTTNEL-----GQSTISRRS---SDPNLTVESIVTDCFNANSNSMFDIRSEANNSVSE 726
            .:..:: :.|.||     .:|...:.|   .:|:|..   |.|...|...|     |.|:|...:
Mouse   575 IKQCKNGILTKELLHAVHPESPALKTSLCLKEPSLLP---VKDTLRAIEGS-----SPADNRYCD 631

  Fly   727 NVQESVKDSKEV 738
            ..:|..|....|
Mouse   632 YAEEFSKSEPTV 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3632	NP_001096996.1	PH-like	35..147	CDD:473070	28/107 (26%)
		Myotub-related	221..591	CDD:461958	125/370 (34%)
		FYVE_MTMR4	1162..1221	CDD:277272
Mtmr6	NP_001388129.1	PH-GRAM_MTMR6	1..101	CDD:270151	24/93 (26%)
		PTP_DSP_cys	130..469	CDD:475123	117/355 (33%)