Protein Alignment CG3632 and mtmr8

DIOPT Version :10

• Sequence 1: NP_001096996.1
• Gene: CG3632 / 32589
• FlyBaseID: FBgn0030735
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: XP_004915812.2
• Gene: mtmr8 / 100489239
• XenbaseID: XB-GENE-948866
• Length: 676
• Species: Xenopus tropicalis
• Alignment Length: 811
• Identity: 199/811 - (24%)
• Similarity: 329/811 - (40%)
• Gaps: 204/811 - (25%)

  Fly    50 ESIKYLGRTDD-----GILALSNYRIFLSKQSTG--YETYVP---LGLIESVQVRDL-FQLIVNC 103
            |::|...|..:     |.|.|:...:...:...|  .||::|   :.|:|.:.:... ..|::.|
 Frog    10 ENVKLFDRYTNKRPAVGTLYLTATHLIYVESGVGARKETWIPHHHISLVEKLALNTTGCPLVIRC 74

  Fly   104 KDASTVRCSFPSAEQCSDWQRRIH------LMIGVPESLETLFAFPFYSWTCDVLGSGNGSGIVS 162
            |       :|.:|......:|..|      |.:..|...|.|:||.:
 Frog    75 K-------NFRAAHFVIQRERDCHKVYTSLLKLSQPAKYEDLYAFSY------------------ 114

  Fly   163 AQANGNGLIAKDRCLTLHNGLAKPTANVTASNPLPDPASETISAAMSNRLQRSVRYES-DFKNEV 226
                                           ||..|            :.:|:|.::. |.:.|.
 Frog   115 -------------------------------NPSHD------------KDERAVGWKQVDLEVEF 136

  Fly   227 ARLGFDLKGSWRISTANADFKLCPSYPPKLLVPCCITDEMLHNVANFRGSRRLPAVVWRHQKSGA 291
            .|:|.. ...|:::..|.|:|:|.:||..|:||....:..:...|.||...|.|.:.:..:.:.|
 Frog   137 LRMGIP-NEFWKLTDLNKDYKVCSTYPTCLVVPKEANEATILGSAKFRSRGRFPVLSYYFKDNNA 200

  Fly   292 ILARCSQPEVGWLGWRNTRDEQLLKALADACAFDRGEHARHSTCANAKAQPTKGSKETNGQSGLS 356
            ::.|||||..|:.. |...||::|:.:                   .||.|
 Frog   201 VICRCSQPLSGFSA-RCEDDEKMLETI-------------------GKANP-------------- 231

  Fly   357 GKSSPSLDDSSHEELTLDEIKKILIVDARSYTSAVTNRARGGGCECIEYYPCAEIEFMNLGNIHA 421
              .||.:                .:||.|...:|:.|||.|.|.|..:.||....:|:.:.|||.
 Frog   232 --GSPFM----------------YVVDTRPKLNAMANRAAGKGYENEDNYPNIRFKFIGIENIHV 278

  Fly   422 IRKSFHAVRQLC-ASSPDDPNWYGQLEKTMWMQHLSGLLGATMTVVHTIEKNGRPVLVHCSDGWD 485
            :|.|...:.::| ..||...|:...||.:.|::|:..::.|.:.:...::.....||||||||||
 Frog   279 MRNSLQKLLEVCEMKSPSMSNFLTVLENSGWLRHIKAVMDAGVFLAKVVQDENASVLVHCSDGWD 343

  Fly   486 RTPQIVATAQLCLDPYYRTVEGFRVLVEREWLNFGHKFADRSGN-GPNSDEVNERCPVFLQWLDL 549
            ||.|:.:.|.:.|||:|||::||..|:|:||::.||||..|.|: ..:..||:   |||.|:::.
 Frog   344 RTAQVCSLASILLDPFYRTIKGFMFLIEKEWISLGHKFTQRCGHLDVDPKEVS---PVFTQFVEC 405

  Fly   550 VHQIHRQYPCSFEFSISYLIKLAQHSLSCLFGTFLCNSLRERIENSVFDRTFSVWPFLAETM--Y 612
            |..:..|:||:||||..:|:::..|..||.||.|:.||.:||.|..:|:||.|:|.||.:..  :
 Frog   406 VWHLTEQFPCAFEFSERFLLEIHDHIFSCQFGNFIGNSQKEREELKIFERTHSLWQFLLQRKQEF 470

  Fly   613 RNPLYKHETEKVLWPAHSVRFLY-FWSDVYLGSLGNKNGTDLPLLSNERQSGHNGLMAKTRSSED 676
            .||||.|...|.|.|. ::.|.: ||..:|       |..|
 Frog   471 VNPLYTHLAYKTLRPI-TLPFTFKFWCGMY-------NRFD------------------------ 503

  Fly   677 LTTNELGQSTISRRSSDPNLTVESIVTDCFNANSN-SMFDIRSEANNSVSENVQESVKDSKEVEL 740
                         :...|...|...:.:|.|..:. ...:|.:|...:..:..::.......|.|
 Frog   504 -------------KGMHPRQCVLDYLLECMNKKAALEKSEIEAENKLAAQDFPEKKGPSVLSVHL 555

  Fly   741 DVTDATEVGPCGRSNNPIPDFHNDQSTASKRDILEVESQTQRRSSLESSQLIPGSVFIFGSSEND 805
            .....|||    .:|..||:...:::.....:....:|......:||::|.:.....:.|..||:
 Frog   556 QTVPTTEV----MANKDIPELSKEETKCQLSNGSMTDSDHNLIETLENNQSVSNGHNVTGEVENN 616

  Fly   806 KNA-----VPSESEE--SLATSQKLNSESGR 829
            .:.     |..|.|.  |:|....:..|..|
 Frog   617 LSVANGHNVTGEVENNLSVANGHNVTGEEDR 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3632	NP_001096996.1	PH-like	35..147	CDD:473070	25/113 (22%)
		Myotub-related	221..591	CDD:461958	117/371 (32%)
		FYVE_MTMR4	1162..1221	CDD:277272
mtmr8	XP_004915812.2	PH-like	1..103	CDD:473070	20/99 (20%)
		PTP-MTMR8	126..433	CDD:350432	110/362 (30%)