Protein Alignment CG3632 and mtmr4

DIOPT Version :9

• Sequence 1: NP_001096996.1
• Gene: CG3632 / 32589
• FlyBaseID: FBgn0030735
• Length: 1250
• Species: Drosophila melanogaster
• Sequence 2: XP_004911826.1
• Gene: mtmr4 / 100151726
• XenbaseID: XB-GENE-986315
• Length: 1093
• Species: Xenopus tropicalis
• Alignment Length: 1252
• Identity: 418/1252 - (33%)
• Similarity: 632/1252 - (50%)
• Gaps: 237/1252 - (18%)

  Fly    13 GSPPPSICFIRAAESYPKSQMEKEDSQLFVPFQELAGESIKYLGRTDDGILALSNYRIFLS-KQS 76
            |..|||:.:|:|.:.:|..::.||:.:|.|||..|.||.::|||..:|.::|:||||:.:. |.|
 Frog    17 GDEPPSLEYIQAKDLFPPRELVKEEEKLQVPFPVLPGEGVEYLGSANDAVIAISNYRLHIKFKDS 81

  Fly    77 TGYETYVPLGLIESVQVRDLFQLIVNCKDASTVRCSFPSAEQCSDWQRRIHLMIGVPESLETLFA 141
            .   ..|||.:||:|:.||:|||.:.|||:..|||.|.:.:||.:|.:|:......|...|.|||
 Frog    82 V---INVPLRMIEAVESRDMFQLQIICKDSKVVRCHFSTFKQCQEWLKRLSRATLRPAKQEDLFA 143

  Fly   142 FPFYSWTCDVLGSGNGSGIVSAQANGNGLIAKDRCLTLHNGLAKPTANVTASNPLPDPASETISA 206
            |.:::| |                  .|:...:....:|  |.:|..:|
 Frog   144 FAYHAW-C------------------QGICTDEEEPLIH--LCRPGDHV---------------- 171

  Fly   207 AMSNRLQRSVRYESDFKNEVARLGFDLKGSWRISTANADFKLCPSYPPKLLVPCCITDEMLHNVA 271
                        :|.|:.|:.|:||||:.:||:|..|.::|||||||.|||||..|||:.|.|||
 Frog   172 ------------KSRFQMELVRMGFDLQNAWRVSEINNNYKLCPSYPQKLLVPVWITDKELENVA 224

  Fly   272 NFRGSRRLPAVVWRHQKSGAILARCSQPEVGWLGWRNTRDEQLLKALADACAFDRGEHARHSTCA 336
            :||..:|:|.||:||.::||::|||||||:.|.||||..||.|:.::|.|||.:......:...:
 Frog   225 SFRSWKRIPVVVYRHTRTGAVIARCSQPEISWWGWRNADDEYLVTSIAKACALNPAVRMPNGNAS 289

  Fly   337 NAKAQPTKGSKETNGQSGLS-----GKSSPSLDDSSHEELTLDEIKKILIVDARSYTSAVTNRAR 396
            :.:.:....:.:|:..|.|:     |...|               :|:|||||||||:||.|||:
 Frog   290 SKENKDGSDNSDTDFDSSLTACPVEGGGVP---------------QKLLIVDARSYTAAVANRAK 339

  Fly   397 GGGCECIEYYPCAEIEFMNLGNIHAIRKSFHAVRQLCASSPDDPNWYGQLEKTMWMQHLSGLLGA 461
            ||||||.||||..|:.||.:.|||:||.||..:|.:|...||..||...||.|.|:||||.:|.|
 Frog   340 GGGCECEEYYPNCEVAFMGMANIHSIRNSFQYLRAVCNQVPDPGNWLSALESTKWLQHLSAMLKA 404

  Fly   462 TMTVVHTIEKNGRPVLVHCSDGWDRTPQIVATAQLCLDPYYRTVEGFRVLVEREWLNFGHKFADR 526
            ...|.:.:::..||||||||||||||||||:.|:|.|||||||:|||:||||.:||::|||||||
 Frog   405 ATVVANAVDREERPVLVHCSDGWDRTPQIVSLAKLLLDPYYRTLEGFQVLVETDWLDYGHKFADR 469

  Fly   527 SGNGPNSDEVNERCPVFLQWLDLVHQIHRQYPCSFEFSISYLIKLAQHSLSCLFGTFLCNSLRER 591
            .|:..|:::.||:|||||||||.:||:..|:||.|||:.::|:||.||:.|||:||||.|:|.||
 Frog   470 CGHQENTEDQNEQCPVFLQWLDCIHQLLLQFPCHFEFNHAFLVKLVQHTYSCLYGTFLANNLCER 534

  Fly   592 IENSVFDRTFSVWPFL--AETMYRNPLYKHETEKVLWPAHSVRFLYFWSDVYLGSLG-------- 646
            ...:::.||.|||..|  ....:.|.||...::.||.|...||.|..|:.|||.:..
 Frog   535 EMRNIYKRTCSVWSLLRTGNKNFHNLLYMPGSDLVLHPVCHVRALQLWTAVYLPATSPCTPMDDR 599

  Fly   647 -------NKNGTDLPLLSNERQSGHNGLMAKTRSSEDLTTNELGQSTISRRSSDPNLTVESIVTD 704
                   ...|.:....|.:|       :.||||.::|.|...|...::|.||||||..:.|:..
 Frog   600 MEMYLTPASQGPEFNARSLDR-------LPKTRSMDNLLTACDGGGLLTRTSSDPNLNHQGILEP 657

  Fly   705 CFNA---NSNSMFDIRSEANNSVSENVQESVK--DSKEVELDVTDATEVGPCGRSNNPIPDFHND 764
            |.::   |...:.||:.:|   :|...:|..:  |||..|.:..|..|..  .::||......|.
 Frog   658 CSSSKEGNETEIHDIQQQA---LSTEPKEEGRDLDSKSTECENKDTGEFR--NQTNNEQNALKNS 717

  Fly   765 QSTASKRDILEVESQTQRR----SSLESSQLIPGSVFIFGSSENDKNAVPSESEESLATSQKLNS 825
            .|.|      :::|...||    |.||::.:||               |||    ::.|.:..||
 Frog   718 LSVA------KLDSVDDRRDHFKSVLENNSVIP---------------VPS----NIGTIKDDNS 757

  Fly   826 ESGRPFFIFGSSENDQSPVPLKSEDTSDISRALWHGAIETSTDTLIPAEPVQKPNSDNSSRDHIT 890
            .|        :..:...|||:          .:.:|:::            .||..|.|....::
 Frog   758 HS--------NGISGHLPVPV----------LVTNGSVQ------------NKPCVDVSKAMKLS 792

  Fly   891 SPTMELVSGDRKLE-STSTVQASKISQSYNNLPKVHIRPNAVICPQRVDAFPHHLDLQVPRETTG 954
            :   ||...|:|.. .|...:.|..:.::::||  .:..:..:|         .:.|:.|
 Frog   793 T---ELSRTDKKPGFQTQRDEFSLFASNWDSLP--GMMRSVPLC---------EVGLRRP----- 838

  Fly   955 NPDRCKPEKLAKDANANANANGSLLASDGYNGEESLFISPDLQRFVGQSPFDAPSTGGRIRRNTF 1019
                     |:.|.:..:..|        .||..:..::.:|     .:.|..|        ..|
 Frog   839 ---------LSYDCSTRSQHN--------RNGRHTTKLTGNL-----PASFHCP--------GLF 873

  Fly  1020 GSSYSRDMKFTAENGSAHQFPSSGIISLPPTPFQERAQFTISCPDGLAHGLSEQNIRLHQIVQEH 1084
            ..|....|....:...:.:|......|..|..:|:        .|||.........||.|:...:
 Frog   874 TKSCRCVMACHTKQIQSGRFLPLACPSPAPLIYQD--------DDGLPIPSDVVQQRLRQMEASY 930

  Fly  1085 KLREEMLLREIHGMRLAL-LEKGCPSCNSIVS------TNMEHENGSDIVENASTCSWEAVEERS 1142
            |...::|.|::..::|.| :.:.|...:...:      |.::..:|||:.:..|..|    |:|.
 Frog   931 KQEVDLLRRQVWELQLQLEIRQYCAPPSEPEADYEDDFTCVKESDGSDMDDLYSDKS----EDRL 991

  Fly  1143 GPASYAPSSIQEKKASSVLWVPDHAVSRCSSCQTEFWLGRRKHHCRSCGEIFCADCSEFWAPLPN 1207
            ..||:.|  :.:|:.....|||||..|.|.:|..||||.:|:||||:||.:|||.|.....|:|:
 Frog   992 SEASWEP--VDKKETEVTRWVPDHMASHCFNCDCEFWLAKRRHHCRNCGNVFCAACCHLKLPIPD 1054

  Fly  1208 EKLFNPVRLCGSCYTSV 1224
            ::|::||.:|.:||..:
 Frog  1055 QQLYDPVLVCNTCYDHI 1071

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3632	NP_001096996.1	PH-like	35..147	CDD:302622	48/112 (43%)
		Myotub-related	221..590	CDD:284109	194/373 (52%)
		FYVE_MTMR4	1162..1221	CDD:277272	29/58 (50%)
mtmr4	XP_004911826.1	PH-GRAM_MTMR4	37..150	CDD:270150	49/116 (42%)
		PTP-MTMR4	188..495	CDD:350435	165/321 (51%)
		FYVE_MTMR4	1009..1068	CDD:277272	29/58 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	457	1.000	Domainoid score	I490
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	683	1.000	Inparanoid score	I699
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D191120at33208
OrthoFinder	1	1.000	-	-		FOG0004824
OrthoInspector	1	1.000	-	-		otm47592
Panther	1	1.100	-	-	O	PTHR10807
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2890
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.070