DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9911 and MPD1

DIOPT Version :9

Sequence 1:	NP_573111.1	Gene:	CG9911 / 32588	FlyBaseID:	FBgn0030734	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_014931.3	Gene:	MPD1 / 854462	SGDID:	S000005814	Length:	318	Species:	Saccharomyces cerevisiae

Alignment Length:	164	Identity:	40/164 - (24%)
Similarity:	74/164 - (45%)	Gaps:	28/164 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 MTSDNIDMTL-ASNELVFLNFYAEWCRFSNILAPIFAEAADKIKEEFPEAGKVVLGKVDCD--KE 99
            :|..:.|..: .:|....:.|||.||.....|:..|.:||.::.      |.|.:..|:||  |.
Yeast    34 LTPKSFDKAIHNTNYTSLVEFYAPWCGHCKKLSSTFRKAAKRLD------GVVQVAAVNCDLNKN 92

  Fly   100 TAIASRFHINKYPTLKIVRNGQ--LSK--------------REYRGQRSAEAFLEFVKKQLEDPI 148
            .|:.:::.:|.:|||.:.|..:  |||              ..|.|.|:....::|...::...:
Yeast    93 KALCAKYDVNGFPTLMVFRPPKIDLSKPIDNAKKSFSAHANEVYSGARTLAPIVDFSLSRIRSYV 157

  Fly   149 QEFKSLKDLENLDSKK-RLILGYFDRRDQ--PEY 179
            ::|..:..|.:|..|. :|.:..|.::|:  |.|
Yeast   158 KKFVRIDTLGSLLRKSPKLSVVLFSKQDKISPVY 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9911	NP_573111.1	PDI_a_ERp44	33..140	CDD:239294	30/120 (25%)
		PDI_b_ERp44	148..241	CDD:239368	9/35 (26%)
		Thioredoxin_6	171..357	CDD:290560	4/11 (36%)
		PDI_b'_ERp44	252..362	CDD:239370
MPD1	NP_014931.3	ER_PDI_fam	30..>275	CDD:273457	40/164 (24%)
MPD1	NP_014931.3	PDI_a_MPD1_like	30..150	CDD:239300	31/121 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910