Protein Alignment ERp44 and EUG1

DIOPT Version :10

• Sequence 1: NP_573111.1
• Gene: ERp44 / 32588
• FlyBaseID: FBgn0030734
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: NP_010806.1
• Gene: EUG1 / 852130
• SGDID: S000002926
• Length: 517
• Species: Saccharomyces cerevisiae
• Alignment Length: 423
• Identity: 99/423 - (23%)
• Similarity: 174/423 - (41%)
• Gaps: 78/423 - (18%)

  Fly    16 ALVAILQLLQYTQPADAAGAVP------MTSDNIDMTLASNELVFLNFYAEWCRFSNILAPIFAE 74
            |:|:......:|...::|.|.|      :|.......:.|:.||.:.|:|.||..|.||.|...|
Yeast    10 AIVSFCLFASFTLAENSARATPGSDLLVLTEKKFKSFIESHPLVLVEFFAPWCLHSQILRPHLEE 74

  Fly    75 AADKIKEEFPEAGKVVLGKVDCDKETAIASRFHINKYPTLKIVRNGQL-SKREYRGQRSAEAFLE 138
            ||..:||.     .|.:.::||:..:.:..:..||.||||||.:||:: ..:.|||.:..:...:
Yeast    75 AASILKEH-----NVPVVQIDCEANSMVCLQQTINTYPTLKIFKNGRIFDGQVYRGVKITDEITQ 134

  Fly   139 F---------VKKQLEDPIQEFKSLKDLENLDSK---KRLILGYFDRRDQPEYDIFRKVATNLKE 191
            :         :....||.||.:     |||....   .|.:.|.        .:.:::||.:|.|
Yeast   135 YMIQLYEASVIYLNSEDEIQPY-----LENATLPVVINRGLTGL--------NETYQEVALDLAE 186

  Fly   192 DCQF--HVGFGDAAQAMHPPGT--PIIVFRPDVALSHENDETYTGSLQNFDELKIWVQEKCVPLV 252
            |..|  .:...|.:.::|.|.|  ||        |...|.::..|   |...|..|::...:|..
Yeast   187 DYVFLSLLDSEDKSLSIHLPNTTEPI--------LFDGNVDSLVG---NSVALTQWLKVVILPYF 240

  Fly   253 REITFENAEELTEEGLPFLILFHHPTDHNSIKDYKSIIERQLLDEKQNVNFLTADGKRFAHPLHH 317
            .:|..:...:.....||....|:  |....::||..:..:...:.:..:||:..:...|.|.:..
Yeast   241 TDIEPDLFPKYISSNLPLAYFFY--TSEEELEDYTDLFTQLGKENRGQINFIALNSTMFPHHVRF 303

  Fly   318 LGKSEDDLPLIAIDSFKHMYLFPHFSDMYSPGKLKQFLQDLYSGKLHREFHYGPDPSND---IEP 379
            |...| ..||.||.:..:...:          .|.|..::.|: ||.:     |.|.:.   ::.
Yeast   304 LNMRE-QFPLFAIHNMINNLKY----------GLPQLPEEEYA-KLEK-----PQPLDRDMIVQL 351

  Fly   380 DPHTGKGTSPPESKFKELGPSKHR---YTLLEK 409
            .....:||:.|..|.:|: |.:.:   |.::.|
Yeast   352 VKDYREGTAKPIVKSEEI-PKEQKSNVYKIVGK 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERp44	NP_573111.1	PDI_a_ERp44	33..140	CDD:239294	36/122 (30%)
		PDI_b_ERp44	148..241	CDD:239368	23/99 (23%)
		PDI_b'_ERp44	252..362	CDD:239370	20/109 (18%)
EUG1	NP_010806.1	ER_PDI_fam	33..487	CDD:273457	93/400 (23%)