DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9911 and Txndc16

DIOPT Version :9

Sequence 1:NP_573111.1 Gene:CG9911 / 32588 FlyBaseID:FBgn0030734 Length:412 Species:Drosophila melanogaster
Sequence 2:NP_001297463.1 Gene:Txndc16 / 70561 MGIID:1917811 Length:820 Species:Mus musculus


Alignment Length:364 Identity:76/364 - (20%)
Similarity:145/364 - (39%) Gaps:67/364 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 AVPMTSDNIDMTLASNELVFLNFYAEWCRFSNILAPIFAEAADKIKEEFPEAGKVVLGKVDCDKE 99
            :|.:|.:..:.|:.:::.:.| |||.|...|......:.:.|.|:|..    ..::|.:::|...
Mouse   394 SVELTEETFNTTVMTSDSIVL-FYATWHAVSMAFLQSYIDVAIKLKGR----STILLTRINCADW 453

  Fly   100 TAIASRFHINKYPTLKIVRNGQLSKREYRGQRSAEAFLEFVK-KQLEDP-----IQEFKS----- 153
            :.|.::.::..:|.:|:.:.|: |...|.|..:.:..|:|:: .::..|     |||.:.     
Mouse   454 SDICTKQNVTAFPVVKLYKEGE-SPVSYAGMLATKDLLKFI
QLNKISCPVNIASIQEAEKYLRGE 517

  Fly   154 -LKDLENLDSKKRLILGYFDRRDQPEYDIFRKVATNLKEDCQFHVGFGDAAQAMHPPGTPIIVFR 217
             .|||.:  |....:||.|........::||:....|:         |.....::......|:..
Mouse   518 LYKDLPS--SASVSVLGLFSPAMASAKELFREAGKQLR---------GSVITGIYSEDDVWILSN 571

  Fly   218 ------PDVALSHENDETYTGSLQNFDELKIWVQEKCVPLVREITFENAEELTEEGLPFLILFHH 276
                  |.:.|:...:    |.:::.......||:....|...: .|...|:|.|.||..:.|..
Mouse   572 KYATTLPALLLARPKE----GRIESVPLDTTLVQDMAQILANAL-LEAFPEITVENLPTYLRFQR 631

  Fly   277 PT----DHNSIK-DYKSIIERQLLDEKQNVNFL--------TADGKRFAHPLHHLGKSEDDLP-- 326
            |.    ...||. .|::.| ..|:.:||..:|.        |..|:.....  :.|:    ||  
Mouse   632 PLLLLFSGGSINPQYRNTI-LALVRQKQLDSFTPCWLNLKNTPVGRGILKA--YFGR----LPPL 689

  Fly   327 ----LIAIDSFKHMYLFPHFSDMYSPGKLKQFLQDLYSG 361
                |:.:.|...:|.||. |...:...|..:|:.|.:|
Mouse   690 PQLLLVNLHSGGQVYAFPS-SQSVTEQSLVLWLKHLQAG 727

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9911NP_573111.1 PDI_a_ERp44 33..140 CDD:239294 22/104 (21%)
PDI_b_ERp44 148..241 CDD:239368 18/104 (17%)
Thioredoxin_6 171..357 CDD:290560 41/210 (20%)
PDI_b'_ERp44 252..362 CDD:239370 31/129 (24%)
Txndc16NP_001297463.1 ER_PDI_fam 65..493 CDD:273457 22/104 (21%)
PDI_a_family 395..493 CDD:239259 22/103 (21%)
Thioredoxin_6 534..722 CDD:372755 40/209 (19%)
Mediates endoplasmic reticulum retention. /evidence=ECO:0000250|UniProtKB:Q9P2K2 817..820
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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