DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9911 and zgc:136472

DIOPT Version :9

Sequence 1:	NP_573111.1	Gene:	CG9911 / 32588	FlyBaseID:	FBgn0030734	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001035331.1	Gene:	zgc:136472 / 678514	ZFINID:	ZDB-GENE-060421-2552	Length:	510	Species:	Danio rerio

Alignment Length:	391	Identity:	84/391 - (21%)
Similarity:	156/391 - (39%)	Gaps:	52/391 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 CVALVAILQLLQYTQPADAAGAVPMTSDNIDMTLASNELVFLNFYAEWC--RFSNILAPIFAEAA 76
            |:.|...|...|.....:....:.:|..|....|..:|.:.::|||...  ...:||.  |.|||
Zfish    12 CLFLHQTLAESQSNSIVEDKDVLVLTKSNFHRALKQHEQLLVHFYAPLSGQSLGSILE--FREAA 74

  Fly    77 DKIKEEFPEAGKVVLGKVDCDKETAIASRFHINKYPTLKIVRNGQLSKREY-RGQRSAEAFLEFV 140
            ..:||...:   |.||.||..||..:|...:|...|::::..:|..:...| ...:|:.:.|.::
Zfish    75 GALKEADSD---VKLGGVDVKKEKELAESLNITTLPSIRLYLSGDKNNPVYCPVLKSSASILTWL 136

  Fly   141 KKQLEDPIQEFKSLKDLEN-LDSKKRLILGYFDRRDQPEYDIFRKVATNLKEDCQFHVGFGDAAQ 204
            |::.........::..||| |...:.::|..|...::....:|.:.|.::.:     :.||  ..
Zfish   137 KRRAGPSADIISNVTQLENFLRRDELVVLALFKDLEEGAVKVFYETAADVAD-----LPFG--VT 194

  Fly   205 AMHPPGTPIIVFRPDVALSHEN---------DETYTGSLQNFDELKIWVQEKCVPLVREITFENA 260
            ..|...:...:.|..|.|..::         ..|....|.:|  ::::..|    ||.|.....|
Zfish   195 RHHEVFSKFEISRDSVLLIRKSKLDQQFEMESSTVKTDLVHF--IRLYEME----LVTEYNGVTA 253

  Fly   261 EE-LTEEGLPFLILFHHPTD------HNSIKDYKSIIERQLLDEKQNVNFLTADGK--RFAHPLH 316
            .: |....|..|:||...|:      :|:   |::..||    .:..|.|:..|..  |....:.
Zfish   254 SKILNSVILNHLLLFISKTEGGFEEIYNA---YETTAER----FRGKVLFVLIDVSELRNGRMME 311

  Fly   317 HLGKSEDDLPLIAIDSFKH--MYLFPHFSDMYSPGKLKQFLQDLYSGKLHREFHYGPDPSN-DIE 378
            :.....::.|.:.:.:..:  .|..|  ||.:....|.:|..:...||:..:....|.|:| |.:
Zfish   312 YFHVRSEEAPQVRMVNLSNNLQYQLP--SDQFDTHTLMEFCLNYLDGKVKPKMQSEPVPANWDTQ 374

  Fly   379 P 379
            |
Zfish   375 P 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9911	NP_573111.1	PDI_a_ERp44	33..140	CDD:239294	29/109 (27%)
		PDI_b_ERp44	148..241	CDD:239368	17/102 (17%)
		Thioredoxin_6	171..357	CDD:290560	38/205 (19%)
		PDI_b'_ERp44	252..362	CDD:239370	24/120 (20%)
zgc:136472	NP_001035331.1	ER_PDI_fam	31..478	CDD:273457	80/372 (22%)
		PDI_a_family	34..122	CDD:239259	26/92 (28%)
		PDI_b_family	147..240	CDD:239279	17/101 (17%)
		PDI_b'_family	252..354	CDD:239280	22/110 (20%)
		PDI_a_PDI_a'_C	375..477	CDD:239293	1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910