DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9911 and pdia5

DIOPT Version :9

Sequence 1:	NP_573111.1	Gene:	CG9911 / 32588	FlyBaseID:	FBgn0030734	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001107048.1	Gene:	pdia5 / 556162	ZFINID:	ZDB-GENE-030521-5	Length:	528	Species:	Danio rerio

Alignment Length:	409	Identity:	87/409 - (21%)
Similarity:	151/409 - (36%)	Gaps:	125/409 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 QYTQPA----------DAAGAVPMTSDN---IDMTLASNEL------------VFLNFYAEWCRF 64
            :|.:||          |.||| |:..:|   .|:....:|.            :.:.|||.||..
Zfish   129 EYNRPATFKSMVAFLKDPAGA-PLWEENPEAKDVVHIESEKDFRKLLKREERPILMMFYAPWCGV 192

  Fly    65 SNILAPIFAEAADKIKEEFPEAGKVVLG--KVDCDKETAIASRFHINKYPTLKIVRNGQ-LSKRE 126
            ...:.|||.:||.:.|      ||.||.  .|...:...:...|.:..|||......|: |...|
Zfish   193 CKRMQPIFQQAATETK------GKYVLAGMNVHPAEFDGVKQEFSVKGYPTFCYFEKGKFLHHYE 251

  Fly   127 YRGQRSAEAFLEFVK-------KQLEDPIQEFKS----LKDLENLDS-----KKRLILGYFD--- 172
            ..|..|.: ..:::|       |..|.|..|..|    |.| ::.||     ...||:.|..
Zfish   252 NYGATSKD-ITDWLKNPQPPQPKTPEVPWSESGSAVFHLTD-DSFDSFLEEHPSALIMFYAPWCG 314

  Fly   173 --RRDQPEYDIFRKVATNLKEDCQFHVGFGDAAQAMH-PPGTPIIV--------------FR--- 217
              ::.:||||                    |||:.:: .|.:|.::              |:
Zfish   315 HCKKMKPEYD--------------------DAAETLNKDPNSPGVLAAVDTTIHKSTGERFKISG 359

  Fly   218 -PDVALSHENDETYT-GSLQNFDELKIWVQEKCVP------------LVREITFENAEELTEEGL 268
             |.|....:.:|.|| ..|::.|::..|::....|            .|..:..|:..|..::..
Zfish   360 FPTVKYFEKGEEKYTLPHLRSKDKIIEWLKNPQAPPPPEKSWDEMPSSVSHLGAEDFRESLKKKK 424

  Fly   269 PFLILFHHP-TDH--NSIKDYKSIIERQLLDEKQNVNFLTADGKRFAHPLHHLGKSEDDLPLIAI 330
            ..|::|:.| ..|  |::..:.:..|  :..|.:.:.:...|..:..:  |.|.|.|      .:
Zfish   425 HALVMFYAPWCPHCKNAVPHFTTAAE--MFKEDRKIAYAAVDCTKGQN--HELCKQE------GV 479

  Fly   331 DSFK--HMYLFPHFSDMYS 347
            :.:.  :.|.:..||:.|:
Zfish   480 EGYPTFNYYNYGKFSEKYN 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9911	NP_573111.1	PDI_a_ERp44	33..140	CDD:239294	32/124 (26%)
		PDI_b_ERp44	148..241	CDD:239368	26/126 (21%)
		Thioredoxin_6	171..357	CDD:290560	38/219 (17%)
		PDI_b'_ERp44	252..362	CDD:239370	19/101 (19%)
pdia5	NP_001107048.1	PDI_b_PDIR_N	36..147	CDD:239365	4/17 (24%)
		PDI_a_PDIR	160..264	CDD:239295	27/110 (25%)
		ER_PDI_fam	181..512	CDD:273457	76/356 (21%)
		PDI_a_PDIR	285..388	CDD:239295	24/123 (20%)
		PDI_a_PDIR	407..510	CDD:239295	19/102 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910