Protein Alignment ERp44 and ERp60

DIOPT Version :10

• Sequence 1: NP_573111.1
• Gene: ERp44 / 32588
• FlyBaseID: FBgn0030734
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: NP_725084.2
• Gene: ERp60 / 36270
• FlyBaseID: FBgn0033663
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 400
• Identity: 98/400 - (24%)
• Similarity: 180/400 - (45%)
• Gaps: 47/400 - (11%)

  Fly    30 ADAAGA----VPMTSDNIDMTLASNELVFLNFYAEWCRFSNILAPIFAEAADKIKEEFPEAGKVV 90
            |.::||    :.:..|:...||..:|...:.|||.||.....|.|.:|:||:.:|::.|   .:.
  Fly    15 AISSGAEQDVLELGDDDFATTLKQHETTLVMFYAPWCGHCKRLKPEYAKAAEIVKDDDP---PIK 76

  Fly    91 LGKVDC---DKETAIASRFHINKYPTLKIVRNGQLSKREYRGQRSAEAFLEFVKKQLEDPIQEFK 152
            |.||||   .|||  .|::.::.||||||.|..::| ::|.|.|.|....::::.|:....:..:
  Fly    77 LAKVDCTEAGKET--CSKYSVSGYPTLKIFRQDEVS-QDYNGPREASGIAKYMRAQVGPASKTVR 138

  Fly   153 SLKDLEN-LDSKKRLILGYFDRRDQPEYDIFRKVATNLKEDCQFHVGFGDAAQAMHPPGTP---I 213
            ::.:|:. ||:|...:.|||...|.....||.|.|...:|..:|  |.....:.:...|..   :
  Fly   139 TVAELKKFLDTKDTTLFGYFSDSDSKLAKIFLKFADKNREKYRF--GHSSEKEVLDKQGETDKIV 201

  Fly   214 IVFRPDVALSHENDE-TYTGSLQNFDELKIWVQEKCVPLVREITFENAEELTEEGLPFLILFH-- 275
            ::..|.::...|:.. .:.||.::  :|..:|:|....||...|.::.::...   |.:..::
  Fly   202 LIRAPHLSNKFESSSIKFEGSSES--DLSTFVKENFHGLVGHRTQDSVKDFQN---PLITAYYSV 261

  Fly   276 ----HPTDHNSIKDYKSIIERQLLDEKQNVNFLTADGKRFAHPLHHLGKS-EDDLPLIAIDSFKH 335
                :|...|..::....:.::.:.:   :||..|....|.|.|:..|.. ..|.|::.....|:
  Fly   262 DYQKNPKGTNYWRNRVLKVAKEFVGQ---INFAIASKDDFQHELNEYGYDFVGDKPVVLARDEKN 323

  Fly   336 M-YLFPHFSDMYSPGKLKQFLQDLYSGKLHREFHYGPDP-SNDIEPDPHTGKGTSPPESKFKELG 398
            : |.   ..|.:|...|:.|::.|.:.:|.......|.| |||........|       .|.:|.
  Fly   324 LKYA---LKDEFSVENLQDFVEKLLANELEPYIKSEPIPESNDAPVKVAVAK-------NFDDLV 378

  Fly   399 PSKHRYTLLE 408
            .:..:.||:|
  Fly   379 INNGKDTLIE 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERp44	NP_573111.1	PDI_a_ERp44	33..140	CDD:239294	39/113 (35%)
		PDI_b_ERp44	148..241	CDD:239368	20/97 (21%)
		PDI_b'_ERp44	252..362	CDD:239370	21/117 (18%)
ERp60	NP_725084.2	ER_PDI_fam	23..479	CDD:273457	94/391 (24%)