DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9911 and Pdia5

DIOPT Version :9

Sequence 1:	NP_573111.1	Gene:	CG9911 / 32588	FlyBaseID:	FBgn0030734	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001014147.1	Gene:	Pdia5 / 360722	RGDID:	1359236	Length:	517	Species:	Rattus norvegicus

Alignment Length:	180	Identity:	46/180 - (25%)
Similarity:	80/180 - (44%)	Gaps:	37/180 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ILQLLQYTQP----------ADAAGAV-PMTSDNIDMTLASNELVFLNFYAEWCRFSNILAPIFA 73
            |::.|:..||          ||..|:| .:|.::.|..:..:..|.:.|:|.||.....:.|.|.
  Rat   250 IVEWLKNPQPPQPQVPETPWADEGGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFE 314

  Fly    74 EAADKIKEEFPEAGKVVLGKVDCDKETAIASRFHINKYPTLKIVRNGQLSKREYRGQRSAEAFLE 138
            .||:.:..:...:|  ||..||.....|:|.||||:.:||||..:||:  ::.....|:.:.|:|
  Rat   315 SAAEVLHGDAESSG--VLAAVDATINEALAERFHISAFPTLKYFKNGE--QQAVPALRTKKKFIE 375

  Fly   139 FVKKQLEDPIQE-----------------FKSLKDLENLDSKKRLILGYF 171
            :::.....|..|                 |:     |.|..||..::.::
  Rat   376 WMQNPEAPPPPEPTWEEQQTSVLHLVGDNFR-----ETLKKKKHTLVMFY 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9911	NP_573111.1	PDI_a_ERp44	33..140	CDD:239294	33/107 (31%)
		PDI_b_ERp44	148..241	CDD:239368	6/41 (15%)
		Thioredoxin_6	171..357	CDD:290560	0/1 (0%)
		PDI_b'_ERp44	252..362	CDD:239370
Pdia5	NP_001014147.1	PDI_b_PDIR_N	26..137	CDD:239365
		PDI_a_PDIR	150..254	CDD:239295	1/3 (33%)
		ER_PDI_fam	166..501	CDD:273457	46/180 (26%)
		PDI_a_PDIR	275..377	CDD:239295	32/105 (30%)
		PDI_a_PDIR	396..499	CDD:239295	5/30 (17%)
		Prevents secretion from ER. /evidence=ECO:0000255	514..517
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000