| Sequence 1: | NP_573111.1 | Gene: | CG9911 / 32588 | FlyBaseID: | FBgn0030734 | Length: | 412 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055866.1 | Gene: | ERP44 / 23071 | HGNCID: | 18311 | Length: | 406 | Species: | Homo sapiens |
| Alignment Length: | 377 | Identity: | 194/377 - (51%) |
|---|---|---|---|
| Similarity: | 264/377 - (70%) | Gaps: | 6/377 - (1%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 38 MTSDNIDMTLASNELVFLNFYAEWCRFSNILAPIFAEAADKIKEEFPEAGKVVLGKVDCDKETAI 102
Fly 103 ASRFHINKYPTLKIVRNGQLSKREYRGQRSAEAFLEFVKKQLEDPIQEFKSLKDLENLDSKKRLI 167
Fly 168 LGYFDRRDQPEYDIFRKVATNLKEDCQFHVGFGDAAQAMHPPGTPIIVFRPDVALSHE-NDETYT 231
Fly 232 GSLQNFDELKIWVQEKCVPLVREITFENAEELTEEGLPFLILFHHPTDHNSIKDYKSIIERQLLD 296
Fly 297 EKQNVNFLTADGKRFAHPLHHLGKSEDDLPLIAIDSFKHMYLFPHFSDMYSPGKLKQFLQDLYSG 361
Fly 362 KLHREFHYGPDPSNDIEPDPHTGKGTSPPESKFKELGPSKHRYTLL-EKDEL 412 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG9911 | NP_573111.1 | PDI_a_ERp44 | 33..140 | CDD:239294 | 55/101 (54%) |
| PDI_b_ERp44 | 148..241 | CDD:239368 | 35/93 (38%) | ||
| Thioredoxin_6 | 171..357 | CDD:290560 | 93/186 (50%) | ||
| PDI_b'_ERp44 | 252..362 | CDD:239370 | 65/109 (60%) | ||
| ERP44 | NP_055866.1 | PDI_a_ERp44 | 29..136 | CDD:239294 | 55/101 (54%) |
| PDI_b_ERp44 | 144..234 | CDD:239368 | 35/93 (38%) | ||
| Interaction with ITPR1. /evidence=ECO:0000250 | 236..285 | 32/48 (67%) | |||
| PDI_b'_ERp44 | 245..355 | CDD:239370 | 65/109 (60%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 360..387 | 11/26 (42%) | |||
| Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 | 403..406 | 1/2 (50%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165152616 | |
| Domainoid | 1 | 1.000 | 185 | 1.000 | Domainoid score | I3389 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0912 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H12638 | |
| Inparanoid | 1 | 1.050 | 398 | 1.000 | Inparanoid score | I1958 |
| Isobase | 1 | 0.950 | - | 0.930827 | Normalized mean entropy | S1743 |
| OMA | 1 | 1.010 | - | - | QHG52519 | |
| OrthoDB | 1 | 1.010 | - | - | D318483at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0006584 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41711 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_107572 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR46295 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3277 |
| SonicParanoid | 1 | 1.000 | - | - | X4826 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 17 | 16.750 | |||||