DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment caz and Cirbp

DIOPT Version :9

Sequence 1:	NP_523365.2	Gene:	caz / 32587	FlyBaseID:	FBgn0285954	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	XP_006241075.3	Gene:	Cirbp / 81825	RGDID:	620756	Length:	176	Species:	Rattus norvegicus

Alignment Length:	167	Identity:	58/167 - (34%)
Similarity:	84/167 - (50%)	Gaps:	18/167 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 MITQEDTIFVSGMDPSTTEQDIETHFGAIGIIKKDKRTMKPKIWLYKNKETGASKGEATVTYDDT 179
            |.:.|..:||.|:...|.||.:|..|...|.|.        ::.:.|::||..|:|...||:::.
  Rat     1 MASDEGKLFVGGLSFDTNEQALEQVFSKYGQIS--------EVVVVKDRETQRSRGFGFVTFENI 57

  Fly   180 NAAQSAIEWFDGRDFNGNAIKVSLAQRQNNWNKGGGGGGGGGGRGGF-GGRRGGGG---GGGGGG 240
            :.|:.|:...:|:..:|..|:|..|.:.::....|..||..||||.| |||..|.|   |||..|
  Rat    58 DDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGFFRGGRSRGRGFSRGGGDRG 122

  Fly   241 GGGGRFDRGGGGGGGRYD------RGGGGGGGGGGGN 271
            .|||||:...||.||..|      :||..|....||:
  Rat   123 YGGGRFESRSGGYGGSRDYYASRSQGGSYGYRSSGGS 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
caz	NP_523365.2	RRM	<118..>205	CDD:223796	24/86 (28%)
		RRM_SARFH	122..204	CDD:240978	23/81 (28%)
		zf-RanBP	275..304	CDD:279035
		RanBP2-type Zn finger	279..298	CDD:275375
Cirbp	XP_006241075.3	RRM_CIRBP_RBM3	6..85	CDD:409883	24/86 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000