Protein Alignment caz and ewsr1a

DIOPT Version :10

• Sequence 1: NP_523365.2
• Gene: caz / 32587
• FlyBaseID: FBgn0285954
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_001108610.1
• Gene: ewsr1a / 323597
• ZFINID: ZDB-GENE-030131-2317
• Length: 626
• Species: Danio rerio
• Alignment Length: 468
• Identity: 180/468 - (38%)
• Similarity: 228/468 - (48%)
• Gaps: 91/468 - (19%)

  Fly     2 ERGGYGGGSGQGY---------NNFAVPPPNYQQMPNK-----TGNYNEP--------------- 37
            ::|||.|..| ||         ..:...||..||.|..     :|:|.:|
Zfish   180 QQGGYQGQQG-GYGQQSSYSQQGGYQQTPPQQQQAPPSSYAPPSGSYGQPSASQYGQQGSTGGGY 243

  Fly    38 ------PPN-YG------KQGGGYDSGSGHRGSGGSGNGGGGGGSWN---DRGGNSYG---NGGA 83
                  ||| ||      :.|||| ||....|.||.|.|.|.||..|   .|||...|   .||.
Zfish   244 GQSDYKPPNQYGSYRPDHQNGGGY-SGPESGGYGGPGEGRGMGGGENRGRGRGGFDRGMMRGGGG 307

  Fly    84 SKDSYNKGHGGYSGGGGGGGGGGGGGSGGNDMITQED----TIFVSGMDPSTTEQDIETHFGAIG 144
            .:...::|..|.:|..||....|.|..|..:  .|:|    ||:::|:..:.|.:::...|...|
Zfish   308 MRGGMSRGGMGIAGDRGGFSKPGDGEMGAPE--EQDDSENSTIYITGLTENATLEEVADFFKHSG 370

  Fly   145 IIKKDKRTMKPKIWLYKNKETGASKGEATVTYDDTNAAQSAIEWFDGRDFNGNAIKVSLAQRQNN 209
            ||:.:|||..|.:.:|.:|:||..||:||::|::..:|::|:|||||:||.|..:|||:|:|:..
Zfish   371 IIRINKRTGLPAVNIYTDKDTGKPKGDATLSYEEPPSAKAAVEWFDGKDFQGKKLKVSMARRKPM 435

  Fly   210 WNKGGGGGGGGGGRGGFGGRRG--GGGGGGGGGGGGGRFDRGGGGGGGRYDRGGGGGGGGGGGNV 272
            .....||....|.|||..||.|  |.||.|.||..||...|||..|.||        ||..|||:
Zfish   436 MGMMRGGMPMRGDRGGMMGRGGMMGRGGMGRGGDRGGFMPRGGPRGMGR--------GGPTGGNM 492

  Fly   273 QPRDGDWKCNS--CNNTNFAWRNECNRCKTPKGDDEG-----SSGGGGGGGYGGGGGGGGYDRGN 330
            |.|.|||:|.:  |.|.|||||.|||:||.||.:..|     ..|..|.||.||..||.|.|||.
Zfish   493 QQRAGDWQCPNAGCGNQNFAWRMECNQCKAPKPEGFGPPPFPPGGDRGRGGPGGMRGGRGMDRGG 557

  Fly   331 DRGSGG--GGYHNRDRGGNSQGGGGGGGGGGGYSRFNDNNGG------GRGGRGGGGGNRRD-GG 386
            ..|.||  || ...|||| .:|.|...||.||..|     ||      ||.|||.|...:.| .|
Zfish   558 PGGPGGFRGG-RGVDRGG-FRGRGMDRGGFGGRGR-----GGPPMDDMGRRGRGMGPPGKMDMKG 615

  Fly   387 PMRNDGGMRSRPY 399
            ..|.|  .|.|||
Zfish   616 DHRQD--RRERPY 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caz	NP_523365.2	RRM_SARFH	122..204	CDD:240978	33/81 (41%)
		zf-RanBP	275..304	CDD:395516	19/30 (63%)
		RanBP2-type Zn finger	279..298	CDD:275375	12/20 (60%)
ewsr1a	NP_001108610.1	RRM_EWS	346..429	CDD:409950	33/82 (40%)
		zf-RanBP	495..525	CDD:395516	18/29 (62%)
		RanBP2-type Zn finger	499..520	CDD:275376	12/20 (60%)