Protein Alignment eas and ETNK2

DIOPT Version :9

• Sequence 1: NP_523364.2
• Gene: eas / 32585
• FlyBaseID: FBgn0000536
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001284689.1
• Gene: ETNK2 / 55224
• HGNCID: 25575
• Length: 394
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 150/402 - (37%)
• Similarity: 199/402 - (49%)
• Gaps: 76/402 - (18%)

  Fly    62 PNPSGSENKNENEQNSRDIRAKPEDKSRKEAIVPFVPIFVEEADVIQGAKELLKVIRPTWDLSHV 126
            |.|..|....|....|...|..|...  :.|.|.:..|.|:..|::.||..|::.:||.|....|
Human    21 PCPQCSWGMEEKAAASASCREPPGPP--RAAAVAYFGISVDPDDILPGALRLIQELRPHWKPEQV 83

  Fly   127 EFKSFTDGITNKLVGCFHKEISKLNDENGGSYLPIKTQGLSPVQSEDPVIIEKEDDDEFTDDRAA 191
            ..|.||||||||||.|:                                 :|::..|
Human    84 RTKRFTDGITNKLVACY---------------------------------VEEDMQD-------- 107

  Fly   192 DDGSPVQYSDNVVLVRIYGNKTDLLIDRKAETQNFLLLHTYGLAPSLYATFKNGLVYEYVPGTTL 256
                       .||||:||.:|:||:||:.|.:||.||..:..||.||.||:|||.|||:.|..|
Human   108 -----------CVLVRVYGERTELLVDRENEVRNFQLLRAHSCAPKLYCTFQNGLCYEYMQGVAL 161

  Fly   257 NTDSVLCPEIWPLVARRMAEMHRKVRKHGDSSATKPMPMIWKKTQSFLDLV-----PERFSDAEK 316
            ..:.:..|.::.|:|..||::|   ..|.:.|.  |.|::|.|..::..||     |...:|..|
Human   162 EPEHIREPRLFRLIALEMAKIH---TIHANGSL--PKPILWHKMHNYFTLVKNEINPSLSADVPK 221

  Fly   317 HKRVKETFLPIGRLREEFNKLYEYLEALDSPIVFSHNDLLLGNVIYTQSLNTVNFIDYEYADYNF 381
                      :..|..|...|.|:|..|:||:||.|||||..|:||......|.|||||||.||:
Human   222 ----------VEVLERELAWLKEHLSQLESPVVFCHNDLLCKNIIYDSIKGHVRFIDYEYAGYNY 276

  Fly   382 QAFDIGNHFAEMCGVDEVDYSRYPKREFQLQWLRVYLEEYLQRSNIQNDEVELLYVQVNQFALA- 445
            |||||||||.|..||:||||..||.||.|||||..||:.. :...:...||:.||||||:|||.
Human   277 QAFDIGNHFNEFAGVNEVDYCLYPARETQLQWLHYYLQAQ-KGMAVTPREVQRLYVQVNKFALGP 340

  Fly   446 SHIFWTVWSLLQ 457
            |.:..|:.:.||
Human   341 SCVSSTMTASLQ 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eas	NP_523364.2	ETNK_euk	126..478	CDD:270706	132/338 (39%)
ETNK2	NP_001284689.1	ETNK_euk	83..338	CDD:270706	126/322 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159872
Domainoid	1	1.000	183	1.000	Domainoid score	I3431
eggNOG	1	0.900	-	-		E1_COG0510
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	279	1.000	Inparanoid score	I2917
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54545
OrthoDB	1	1.010	-	-		D301681at33208
OrthoFinder	1	1.000	-	-		FOG0000493
OrthoInspector	1	1.000	-	-		otm40443
orthoMCL	1	0.900	-	-		OOG6_101726
Panther	1	1.100	-	-	O	PTHR22603
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2241
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.770