DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eas and chka

DIOPT Version :9

Sequence 1:	NP_523364.2	Gene:	eas / 32585	FlyBaseID:	FBgn0000536	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001011466.1	Gene:	chka / 496957	XenbaseID:	XB-GENE-5775623	Length:	441	Species:	Xenopus tropicalis

Alignment Length:	513	Identity:	133/513 - (25%)
Similarity:	197/513 - (38%)	Gaps:	181/513 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ISTSGGNPKVMKDSLSLVRQTVNQQTLSLSQSNQVQNQLNSHSNSNSYPNPSGSENKNENEQNSR 78
            |||:||                    |..:|...|:            |...|...|.|:
Frog    19 ISTAGG--------------------LMTAQRGAVE------------PEVLGVTEKQED----- 46

  Fly    79 DIRAKPEDKSRKEA---IVPFVPIFVEEADVIQGAKELLKVIRPTWDLSHVEFKSFTDGITNKLV 140
                .|..|:|::|   ...|:|          ||..:|:..|     .|:..  ...|::|.|.
Frog    47 ----APNPKTRRKAYRWCKEFLP----------GAWRVLEEER-----FHISV--IRGGLSNMLY 90

  Fly   141 GCFHKEISKLNDENGGSYLPIKTQGLSPVQSEDPVIIEKEDDDEFTDDRAADDGSPVQYSDNVVL 205
            .|               .||                   ||:...:::..:            ||
Frog    91 LC---------------SLP-------------------EDEKSLSNEPRS------------VL 109

  Fly   206 VRIYG-------NKTDLLIDRKAETQNFL--------------LLHTYGLAPSLYATFKNGLVYE 249
            :|:||       ||.:   :::.:.|||.              :|....|.|.||..|..|.:.|
Frog   110 LRLYGAILQMSCNKGE---NQETQRQNFFQGAEAMVMESVMFAILAERSLGPKLYGIFPQGRLEE 171

  Fly   250 YVPGTTLNTDSVLCPEIWPLVARRMAEMHRKVRKHGDSSATKPMPMIWKKTQSFLDLVPERFSD- 313
            ::|...|.|..:..|::...:|.:||      |.||       |.|.:.|...:|....|::..
Frog   172 FIPSRKLETSELSLPDLSAEIAEKMA------RFHG-------MNMPFNKEPKWLFGTMEKYLQQ 223

  Fly   314 -------AEKHKRVKETFLPIGRLREEFNKLYEYLEALDSPIVFSHNDLLLGNVIY-----TQSL 366
                   .|.|.|.....|... |.:|...|...|||..||:||.|||...||::.     ....
Frog   224 VLKIKFTRESHTRKLNKILAYD-LSKEMRSLRCLLEATSSPVVFCHNDCQEGNILLLDGRENSEK 287

  Fly   367 NTVNFIDYEYADYNFQAFDIGNHFAEMCGVDEVDY------------SRYPKREFQLQWLRVYLE 419
            ..:..||:||:.||::.|||||||.|..    .||            |:||.|..|:.::..||.
Frog   288 QKLMLIDFEYSSYNYRGFDIGNHFCEWM----YDYTFEKFPFFKATFSKYPTRRQQIHFVNSYLT 348

  Fly   420 EYLQR-SNIQNDEV-----ELLYVQVNQFALASHIFWTVWSLLQAEHSTIDFDYVGYA 471
            |:|.. .||.|:|.     ||| :::|:||||||.||.:||::||:.|:|:|.|:..|
Frog   349 EFLPGFENISNEEQSKLENELL-IEINRFALASHFFWGLWSIVQAKISSIEFGYMPMA 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eas	NP_523364.2	ETNK_euk	126..478	CDD:270706	110/398 (28%)
chka	NP_001011466.1	PLN02236	38..405	CDD:177880	123/460 (27%)
chka	NP_001011466.1	ChoK_euk	76..415	CDD:270705	111/400 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000493
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910