Protein Alignment eas and CHKB

DIOPT Version :10

• Sequence 1: NP_523364.2
• Gene: eas / 32585
• FlyBaseID: FBgn0000536
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_005189.2
• Gene: CHKB / 1120
• HGNCID: 1938
• Length: 395
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 99/317 - (31%)
• Similarity: 155/317 - (48%)
• Gaps: 58/317 - (18%)

  Fly   204 VLVRIYG---NKTDLLIDRKAETQNFLLLHTYGLAPSLYATFKNGLVYEYVPGTTLNTDSVLCPE 265
            ||:|:||   ...|.|:   .|:..|.:|....|.|.||..|..|.:.:|:|...|.|..:..|.
Human   101 VLLRLYGAILQGVDSLV---LESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELREPV 162

  Fly   266 IWPLVARRMAEMHRKVRKHGDSSATKPMPMIWKKTQSFLDLVPERFSDAEKHKRVKETFLPIG-- 328
            :...:|.:||:.|             .|.|.:.|...:|      |...|::.:..:...|.|
Human   163 LSAAIATKMAQFH-------------GMEMPFTKEPHWL------FGTMERYLKQIQDLPPTGLP 208

  Fly   329 --------RLREEFNKLYEYLEALDSPIVFSHNDLLLGNVIY---TQSLNTVNFIDYEYADYNFQ 382
                    .|::|...|.:.||:..||:||.|||:..||::.   .::.:::..:|:||:.||::
Human   209 EMNLLEMYSLKDEMGNLRKLLESTPSPVVFCHNDIQEGNILLLSEPENADSLMLVDFEYSSYNYR 273

  Fly   383 AFDIGNHFAEMCGVDEVDYSR------------YPKREFQLQWLRVYLEEYLQRSNIQNDE---- 431
            .|||||||.|..    .||:.            ||.:|.||.::|.||.|..:...:..:|
Human   274 GFDIGNHFCEWV----YDYTHEEWPFYKARPTDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKL 334

  Fly   432 VELLYVQVNQFALASHIFWTVWSLLQAEHSTIDFDYVGYAFLRYNEYLARKVEFLSL 488
            .|.|.|:|:::|||||.||.:||:|||..|||:|.|:.||..|:..|..:|.:..|:
Human   335 EEDLLVEVSRYALASHFFWGLWSILQASMSTIEFGYLDYAQSRFQFYFQQKGQLTSV 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eas	NP_523364.2	ETNK_euk	126..478	CDD:270706	96/305 (31%)
CHKB	NP_005189.2	ChoK_euk	69..385	CDD:270705	97/309 (31%)