Protein Alignment eas and CHKA

DIOPT Version :9

• Sequence 1: NP_523364.2
• Gene: eas / 32585
• FlyBaseID: FBgn0000536
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001363148.1
• Gene: CHKA / 1119
• HGNCID: 1937
• Length: 467
• Species: Homo sapiens
• Alignment Length: 487
• Identity: 115/487 - (23%)
• Similarity: 191/487 - (39%)
• Gaps: 165/487 - (33%)

  Fly    62 PNPSGSENKNENEQNSRDIRAKPEDKSRKEAIV---PFVPIFVEEADVIQGAKELLKVIRPTWDL 123
            |.|...|              :||.::|:.|.:   .|:|      ...:|.:|         |.
Human    75 PQPPADE--------------QPEPRTRRRAYLWCKEFLP------GAWRGLRE---------DE 110

  Fly   124 SHVEFKSFTDGITNKLVGCFHKEISKLNDENGGSYLPIKTQGLSPVQSEDPVIIEKEDDDEFTDD 188
            .|:..  ...|::|.|..|               .||..|..|    .::|
Human   111 FHISV--IRGGLSNMLFQC---------------SLPDTTATL----GDEP-------------- 140

  Fly   189 RAADDGSPVQYSDNVVLVRIYGNKTDLLI---------------DRKAETQN------------- 225
                         ..||:|:||....::.               ..:|:.:|
Human   141 -------------RKVLLRLYGAILQMVFLIKLWNGKRSCNKEGSEQAQKENEFQGAEAMVLESV 192

  Fly   226 -FLLLHTYGLAPSLYATFKNGLVYEYVPGTTLNTDSVLCPEIWPLVARRMAEMHRKVRKHGDSSA 289
             |.:|....|.|.||..|..|.:.:::|...|:|:.:..|:|...:|.:||..|
Human   193 MFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFH----------- 246

  Fly   290 TKPMPMIWKKTQSFL---------DLVPERFSDAEKHKRVKETF---LPIGRLREEFNKLYEYLE 342
              .|.|.:.|...:|         :::..:|::..:.|::.:..   ||:     |...|...||
Human   247 --GMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPL-----ELENLRSLLE 304

  Fly   343 ALDSPIVFSHNDLLLGNVIYTQSLNT-----VNFIDYEYADYNFQAFDIGNHFAEMCGVDEVDYS 402
            :..||:||.|||...||::..:....     :..||:||:.||::.|||||||.|..    .|||
Human   305 STPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWM----YDYS 365

  Fly   403 ------------RYPKREFQLQWLRVYLEEYLQR-SNIQNDE----VELLYVQVNQFALASHIFW 450
                        :||.::.||.::..||..:... .|:..:|    .|.:.::||:||||||..|
Human   366 YEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLW 430

  Fly   451 TVWSLLQAEHSTIDFDYVGYAFLRYNEYLARK 482
            .:||::||:.|:|:|.|:.||..|::.|..:|
Human   431 GLWSIVQAKISSIEFGYMDYAQARFDAYFHQK 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eas	NP_523364.2	ETNK_euk	126..478	CDD:270706	100/414 (24%)
CHKA	NP_001363148.1	ChoK_euk	111..462	CDD:270705	102/420 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3046
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000493
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.760