Protein Alignment Prosalpha4 and PSMB10

DIOPT Version :10

• Sequence 1: NP_525092.1
• Gene: Prosalpha4 / 32584
• FlyBaseID: FBgn0004066
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_002792.1
• Gene: PSMB10 / 5699
• HGNCID: 9538
• Length: 273
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 58/248 - (23%)
• Similarity: 101/248 - (40%)
• Gaps: 37/248 - (14%)

  Fly    19 LQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSV-AQLQEDRKVRKICMLDNHVVMAFAGLTADA 82
            |:|.:|:   :.|:|..|:...:.|:||.:.::. ..:..|:...||..:...:....||:.|||
Human    30 LKVPHAR---KTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADA 91

  Fly    83 RIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGISCLIGGFDADGSAHLF 147
            .:.......:.:.|.|:......:..:||.:.|...:|     :...|.|.::||.|..| ..|:
Human    92 EMTTRMVASKMELHALSTGREPRVATVTRILRQTLFRY-----QGHVGASLIVGGVDLTG-PQLY 150

  Fly   148 QTEPSGIF--YEYKANATGRSA--KVVREFFEKSYREEEVANEHGAVKLAIRA-LLEVAQSGQNN 207
            ...|.|.:  ..:.|..:|:.|  .|:.:.|:.:...|..   .|.:..|:.| :|....||.|.
Human   151 GVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAA---QGLLVEAVTAGILGDLGSGGNV 212

  Fly   208 LEVAIMENG-KPLKMLD------------------TDVITDYVKIIEKEKEEE 241
            ....|.:.| |.|:.|.                  |.|:|..||.:..|..||
Human   213 DACVITKTGAKLLRTLSSPTEPVKRSGRYHFVPGTTAVLTQTVKPLTLELVEE 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	45/199 (23%)
PSMB10	NP_002792.1	proteasome_beta_type_7	40..227	CDD:239732	45/195 (23%)
		Pr_beta_C	231..267	CDD:463597	8/35 (23%)