Protein Alignment Prosalpha4 and PSMB7

DIOPT Version :10

• Sequence 1: NP_525092.1
• Gene: Prosalpha4 / 32584
• FlyBaseID: FBgn0004066
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_002790.1
• Gene: PSMB7 / 5695
• HGNCID: 9544
• Length: 277
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 59/280 - (21%)
• Similarity: 105/280 - (37%)
• Gaps: 59/280 - (21%)

  Fly     8 AVTIFSPD-----------GHLLQVEYAQEA-----VRK-GSTAVGVRGANCVVLGVEKKSV-AQ 54
            ||::::|.           ..:|:.::|:..     ||| |:|..||...:.:|||.:.::. ..
Human     3 AVSVYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGM 67

  Fly    55 LQEDRKVRKICMLDNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQK 119
            :..|:...||..:..::....||..||..:.........:.|.|:......:....|.:.|:..:
Human    68 VVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFR 132

  Fly   120 YTQSNGRRPFGISCLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYR----E 180
            |     :...|.:.::||.|..| .||:...|.|...:......|..:......||..:|    |
Human   133 Y-----QGYIGAALVLGGVDVTG-PHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEE 191

  Fly   181 EEVANEHGAVKLAIRALLEVAQSGQNNLEVAIMENGKPLKMLD---------------------- 223
            ||..|   .|..||.|.:.......:|:::.::...|    ||
Human   192 EEAKN---LVSEAIAAGIFNDLGSGSNIDLCVISKNK----LDFLRPYTVPNKKGTRLGRYRCEK 249

  Fly   224 --TDVITDYVKIIEKEKEEE 241
              |.|:|:.:..:|.|..||
Human   250 GTTAVLTEKITPLEIEVLEE 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	49/226 (22%)
PSMB7	NP_002790.1	proteasome_beta_type_7	44..232	CDD:239732	43/200 (22%)
		Pr_beta_C	235..271	CDD:463597	7/35 (20%)