Protein Alignment Prosalpha4 and PSMB2

DIOPT Version :10

• Sequence 1: NP_525092.1
• Gene: Prosalpha4 / 32584
• FlyBaseID: FBgn0004066
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_002785.1
• Gene: PSMB2 / 5690
• HGNCID: 9539
• Length: 201
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 41/224 - (18%)
• Similarity: 86/224 - (38%)
• Gaps: 51/224 - (22%)

  Fly    35 VGVRGANCVVLG---VEKKSVAQLQEDRKVRKICMLDNHVVMAFAGLTADARIMINRAQVECQSH 96
            :|::|.:.|::.   |...::.|:::|..  |:..:...:::...|...|........|...|.:
Human     5 IGIQGPDYVLVASDRVAASNIVQMKDDHD--KMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLY 67

  Fly    97 RL----NVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGISCLIGGFDADGSAHLFQTEPSGIFY- 156
            ::    .:.......:..|.:|...:      .|.|:.::.|:.|:|        :.|...::|
Human    68 KMRNGYELSPTAAANFTRRNLADCLR------SRTPYHVNLLLAGYD--------EHEGPALYYM 118

  Fly   157 EYKA-------NATGRSAKVVREFFEKSYREEEVANEHGAVKLAIRALLEVAQSGQNNLEVAIME 214
            :|.|       .|.|..|.:.....:: |....::.|. ||:| :|..||..|
Human   119 DYLAALAKAPFAAHGYGAFLTLSILDR-YYTPTISRER-AVEL-LRKCLEELQ------------ 168

  Fly   215 NGKPLKMLDTDVITDYVKIIEKEKEEELE 243
                 |....::.|..|:||:|....:|:
Human   169 -----KRFILNLPTFSVRIIDKNGIHDLD 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	34/192 (18%)
PSMB2	NP_002785.1	proteasome_beta_type_2	1..192	CDD:239727	40/222 (18%)