DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prosalpha4 and PSMA7

DIOPT Version :9

Sequence 1:	NP_525092.1	Gene:	Prosalpha4 / 32584	FlyBaseID:	FBgn0004066	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_002783.1	Gene:	PSMA7 / 5688	HGNCID:	9536	Length:	248	Species:	Homo sapiens

Alignment Length:	245	Identity:	170/245 - (69%)
Similarity:	203/245 - (82%)	Gaps:	1/245 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVRKICMLDN 69
            ||||:|:|||||||.|||||||||:||||||||||.:.|||||||||||:||::|.|||||.||:
Human     3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKICALDD 67

  Fly    70 HVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGISCL 134
            :|.||||||||||||:||||:||||||||.||||||:|||||:||.|||:|||||||||||||.|
Human    68 NVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISAL 132

  Fly   135 IGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVANEHGAVKLAIRALLE 199
            |.|||.||:..|:||:|||.::.:||||.||.||.||||.||:|.:|.:..:...:||.|:||||
Human   133 IVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIKALLE 197

  Fly   200 VAQSGQNNLEVAIMENGKPLKMLDTDVITDYVKIIEKEKEEELEKKKQKK 249
            |.|||..|:|:|:|...:.||:|:.:.|..||..|||||||. |||||||
Human   198 VVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEEN-EKKKQKK 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	PRK03996	5..231	CDD:235192	154/225 (68%)
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	149/207 (72%)
PSMA7	NP_002783.1	proteasome_alpha_type_7	3..211	CDD:239724	149/207 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	267	1.000	Domainoid score	I1879
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	346	1.000	Inparanoid score	I2313
Isobase	1	0.950	-	0	Normalized mean entropy	S208
OMA	1	1.010	-	-		QHG62217
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0002043
OrthoInspector	1	1.000	-	-		mtm8580
orthoMCL	1	0.900	-	-		OOG6_101207
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2243
SonicParanoid	1	1.000	-	-		X1345
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.820