Protein Alignment Prosalpha4 and PSMA5

DIOPT Version :10

• Sequence 1: NP_525092.1
• Gene: Prosalpha4 / 32584
• FlyBaseID: FBgn0004066
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_002781.2
• Gene: PSMA5 / 5686
• HGNCID: 9534
• Length: 241
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 81/239 - (33%)
• Similarity: 136/239 - (56%)
• Gaps: 10/239 - (4%)

  Fly     3 SRYDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVRKICML 67
            |.|||.|..|||:|.|.|||||.||::.||||:|::.:..|.|.|||:..:.|.|...:.||..:
Human     6 SEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKIVEI 70

  Fly    68 DNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNG-----RR 127
            |.|:..|.:||.|||:.:|::|:||.|:|.....:.:|:|.:|:.::.|..::.:.:.     .|
Human    71 DAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSR 135

  Fly   128 PFGISCLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVANEHGAVKL 192
            |||::.|.||.|..| ..||..:|||.|.:..|.|.|.:::..:...::.|.:.....|  |:|.
Human   136 PFGVALLFGGVDEKG-PQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKE--AIKS 197

  Fly   193 AIRALLEVAQSGQN--NLEVAIMENGKPLKMLDTDVITDYVKII 234
            ::..|.:|.:...|  |:|:|.::.|:...|...:.:.:.:|.|
Human   198 SLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVIKDI 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	76/214 (36%)
PSMA5	NP_002781.2	proteasome_alpha_type_5	8..220	CDD:239722	76/214 (36%)