Protein Alignment Prosalpha4 and PSMA1

DIOPT Version :10

• Sequence 1: NP_525092.1
• Gene: Prosalpha4 / 32584
• FlyBaseID: FBgn0004066
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_683877.1
• Gene: PSMA1 / 5682
• HGNCID: 9530
• Length: 269
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 86/253 - (33%)
• Similarity: 141/253 - (55%)
• Gaps: 19/253 - (7%)

  Fly     3 SRYDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVRKICML 67
            ::||..||::||.|.:.|:|||.|||::||..||::.....||...|::.::|...:|  ||..:
Human    10 NQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQK--KILHV 72

  Fly    68 DNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGIS 132
            |||:.::.||||||||::.|..:.||...|...:.|:.:..:...|....|..||..||||:|:.
Human    73 DNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVG 137

  Fly   133 CLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVANEHGAVKLAIRAL 197
            .||.|:| |...|:|||.||..:::.:|.:.|..::..|.:.|:...|....|.:..||..:|||
Human   138 LLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHGLRAL 201

  Fly   198 LEVAQSGQN----NLEVAIMENGKPLK--MLDTDVITDYVKIIEKEKEEELEKKKQKK 249
            .|...:.|:    |:.:.|:  ||.|:  :.|.|.::.::        |.||::.|:|
Human   202 RETLPAEQDLTTKNVSIGIV--GKDLEFTIYDDDDVSPFL--------EGLEERPQRK 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	75/211 (36%)
PSMA1	NP_683877.1	proteasome_alpha_type_1	12..222	CDD:239718	76/214 (36%)