DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4 and psmb10

DIOPT Version :9

Sequence 1:	NP_525092.1	Gene:	Prosalpha4 / 32584	FlyBaseID:	FBgn0004066	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001002543.2	Gene:	psmb10 / 436816	ZFINID:	ZDB-GENE-040718-278	Length:	276	Species:	Danio rerio

Alignment Length:	225	Identity:	53/225 - (23%)
Similarity:	96/225 - (42%)	Gaps:	19/225 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 DGHLLQVEYAQEAVRK-GSTAVGVRGANCVVLGVEKKSVAQL-QEDRKVRKICMLDNHVVMAFAG 77
            :.:|.:..|:....|| |:|..|:...:.|:||.:.::...: ..|:...||..:..::....||
Zfish    25 EANLSEKGYSAPNARKTGTTIAGLVFKDGVILGADTRATDDMVVADKNCMKIHYIAPNIYCCGAG 89

  Fly    78 LTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGISCLIGGFDADG 142
            :.|||.:.........:.|.|:...|..:..:||   ||||...:..|.  .|.|.::||.|.:|
Zfish    90 VAADAEVTTQMMSSNVELHSLSTGRPPLVAMVTR---QLKQMLFRYQGH--IGSSLIVGGVDVNG 149

  Fly   143 SAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREE-EVANEHGAVKLAIRALLEVAQSGQN 206
             |.|:...|.|.:.:......|..|......||..|:.. |:......|:.||.|.:.......:
Zfish   150 -AQLYSVYPHGSYDKLPFLTMGSGAASAISVFEDRYKPNMELEEAKQLVRDAITAGIFCDLGSGS 213

  Fly   207 NLEVAIMENGKPLKMLDTDVITDYVKIIEK 236
            |:::.::          ||...||::..::
Zfish   214 NVDLCVI----------TDKKVDYLRTYDQ 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	PRK03996	5..231	CDD:235192	52/218 (24%)
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	49/200 (25%)
psmb10	NP_001002543.2	PRE1	40..224	CDD:223711	48/199 (24%)
		proteasome_beta_type_7	43..231	CDD:239732	48/203 (24%)
		Pr_beta_C	237..270	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900