DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4 and psma7

DIOPT Version :9

Sequence 1:	NP_525092.1	Gene:	Prosalpha4 / 32584	FlyBaseID:	FBgn0004066	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_989071.1	Gene:	psma7 / 394668	XenbaseID:	XB-GENE-974596	Length:	248	Species:	Xenopus tropicalis

Alignment Length:	245	Identity:	171/245 - (69%)
Similarity:	201/245 - (82%)	Gaps:	1/245 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVRKICMLDN 69
            ||||:|:|||||||.|||||||||:||||||||||...|||||||||||:||::|.|||||.||.
Frog     3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKEIVVLGVEKKSVAKLQDERTVRKICALDE 67

  Fly    70 HVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGISCL 134
            :|.||||||||||||:||||:||||||||.||||||:|||||:||.|||:|||||||||||||.|
Frog    68 NVFMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISAL 132

  Fly   135 IGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVANEHGAVKLAIRALLE 199
            |.|||.||:..|:||:|||.::.:||||.||.||.||||.||.|.:|.:..:...:||.|:||||
Frog   133 IVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKHYTDEAIETDDLTIKLVIKALLE 197

  Fly   200 VAQSGQNNLEVAIMENGKPLKMLDTDVITDYVKIIEKEKEEELEKKKQKK 249
            |.|||..|:|:|:|...:|||:|:.:.|..||..|||||||. |||||||
Frog   198 VVQSGGKNIELAVMRRDQPLKILNPEEIERYVAEIEKEKEEN-EKKKQKK 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	PRK03996	5..231	CDD:235192	155/225 (69%)
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	149/207 (72%)
psma7	NP_989071.1	proteasome_alpha_type_7	3..211	CDD:239724	149/207 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	259	1.000	Domainoid score	I1952
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	341	1.000	Inparanoid score	I2298
OMA	1	1.010	-	-		QHG62217
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0002043
OrthoInspector	1	1.000	-	-		otm48186
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2243
SonicParanoid	1	1.000	-	-		X1345
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110