DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4 and Psma6

DIOPT Version :9

Sequence 1:	NP_525092.1	Gene:	Prosalpha4 / 32584	FlyBaseID:	FBgn0004066	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_058979.1	Gene:	Psma6 / 29673	RGDID:	61849	Length:	246	Species:	Rattus norvegicus

Alignment Length:	241	Identity:	68/241 - (28%)
Similarity:	123/241 - (51%)	Gaps:	5/241 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SSRYDRAVTIFSPDGHLLQVEYAQEAVRKGS-TAVGVRGANCVVLGVEKKSVAQLQEDRKVRKIC 65
            |:.:||.:|||||:|.|.|||||.:|:.:|. |:|.|||.:|.|:..:||...:|.:...|..:.
  Rat     6 SAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLF 70

  Fly    66 MLDNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRPFG 130
            .:..::.....|:|||:|..:.||:.|..:.:......:.::.:.:.||.:.|.|||:...||.|
  Rat    71 KITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLG 135

  Fly   131 ISCLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVANEHGAVKLAIR 195
            ...::.|.|.:....:::.:|:|.:..:||.|.|........|.||..:::........|:.||.
  Rat   136 CCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAIT 200

  Fly   196 ALLEVAQSG--QNNLEVAI--MENGKPLKMLDTDVITDYVKIIEKE 237
            .|..|....  .:.:||.:  :||.|...:.:.::....|.:.|::
  Rat   201 CLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	PRK03996	5..231	CDD:235192	65/230 (28%)
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	62/212 (29%)
Psma6	NP_058979.1	proteasome_alpha_type_6	8..220	CDD:239723	62/211 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820