DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4 and SPAC6G10.04c

DIOPT Version :9

Sequence 1:	NP_525092.1	Gene:	Prosalpha4 / 32584	FlyBaseID:	FBgn0004066	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_594101.1	Gene:	SPAC6G10.04c / 2542559	PomBaseID:	SPAC6G10.04c	Length:	272	Species:	Schizosaccharomyces pombe

Alignment Length:	255	Identity:	80/255 - (31%)
Similarity:	126/255 - (49%)	Gaps:	28/255 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SRYDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVRKICML 67
            ::||...|.:||.|.|.|||||.||:::||..||:......||...|::..:|...:|  |:..:
pombe     4 NQYDGDATTWSPQGRLHQVEYALEAIKQGSATVGLVSKTHAVLVALKRNAEELSSYQK--KLIRI 66

  Fly    68 DNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGIS 132
            |:|:.:|.|||..|||::.|..:.|..|.:.....|:.:..:...:|:..|..||..||||:|:.
pombe    67 DDHIGIAIAGLAPDARVLSNYMKQEALSSKTLFTRPIPVRRLMSKVAEKAQINTQEYGRRPYGVG 131

  Fly   133 CLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEK-------SYREEEVANEHGAV 190
            .|:.|:|..| .||.:.:|||:..||...:.|..::..|.:.|:       |.|||.:.:
pombe   132 FLVIGYDESG-PHLLEFQPSGLVLEYLGTSMGSRSQSARTYIERNLDTFPDSSREELILS----- 190

  Fly   191 KLAIRALLEVAQSGQNNLE--VAIMENGKPLKMLDTDVITDYVKIIEKEKEEELEKKKQK 248
              |:|||.:.....|...|  |:|...||..|         |....:.:.:|.|:|...|
pombe   191 --ALRALRDTLSKDQELTEENVSISVIGKDEK---------YTLYDQNDTKEWLDKLGDK 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	PRK03996	5..231	CDD:235192	75/234 (32%)
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	71/216 (33%)
SPAC6G10.04c	NP_594101.1	PRE1	4..239	CDD:223711	79/253 (31%)
SPAC6G10.04c	NP_594101.1	proteasome_alpha_type_1	6..216	CDD:239718	72/219 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810