DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4 and Psmb8

DIOPT Version :9

Sequence 1:	NP_525092.1	Gene:	Prosalpha4 / 32584	FlyBaseID:	FBgn0004066	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_034854.2	Gene:	Psmb8 / 16913	MGIID:	1346527	Length:	276	Species:	Mus musculus

Alignment Length:	182	Identity:	34/182 - (18%)
Similarity:	79/182 - (43%)	Gaps:	17/182 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVA-QLQEDRKVRKICMLDNHVVMAFAGLTADA 82
            :|:|.|.     |:|.:..:..:.|::.|:.::.| ......::.|:..::.:::...:|..||.
Mouse    65 VQIEMAH-----GTTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADC 124

  Fly    83 RIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGIS--CLIGGFDADGSAH 145
            :........||:.:.|...:.:::...::.::.:..:|      |..|:|  .:|.|:|..|..
Mouse   125 QYWERLLAKECRLYYLRNGERISVSAASKLLSNMMLQY------RGMGLSMGSMICGWDKKGPG- 182

  Fly   146 LFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVANEHGAVKLAIRAL 197
            |:..:.:|.....:..:||..........:..||::....|  |..|..||:
Mouse   183 LYYVDDNGTRLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEE--AYDLGRRAI 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	PRK03996	5..231	CDD:235192	34/182 (19%)
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	34/182 (19%)
Psmb8	NP_034854.2	PTZ00488	40..271	CDD:185666	34/182 (19%)
Psmb8	NP_034854.2	proteasome_beta_type_5	73..260	CDD:239730	30/169 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900