DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4 and AgaP_AGAP001995

DIOPT Version :9

Sequence 1:	NP_525092.1	Gene:	Prosalpha4 / 32584	FlyBaseID:	FBgn0004066	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	XP_550819.1	Gene:	AgaP_AGAP001995 / 1281126	VectorBaseID:	AGAP001995	Length:	234	Species:	Anopheles gambiae

Alignment Length:	233	Identity:	88/233 - (37%)
Similarity:	139/233 - (59%)	Gaps:	8/233 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SSRYDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVRKICM 66
            |.||..::|.|||.|.|:|:|||..||..|:.:||::..|.||:..|.|..:.|.::..|.|:.|
Mosquito     3 SERYSFSLTTFSPSGKLVQIEYALAAVAAGAPSVGIKAVNGVVIATENKQKSILYDEHSVHKVEM 67

  Fly    67 LDNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGI 131
            :.||:.|.::|:..|.|:::.:|:...|::.|...:|:....:.:.:|.:.|:||||.|.||||:
Mosquito    68 VTNHIGMIYSGMGPDYRLLVKQARKLAQNYYLTYREPIPTSQLVQKVATVMQEYTQSGGVRPFGV 132

  Fly   132 SCLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVANEHGAVKLAIRA 196
            |.||.|:| ||..:|||.:|||.::.:||.|.|::|...:.|.||.|.|:...::  ||..||..
Mosquito   133 SLLICGWD-DGRPYLFQCDPSGAYFAWKATAMGKNANNGKTFLEKRYSEDLELDD--AVHTAILT 194

  Fly   197 LLE--VAQSGQNNLEVAIME-NGKPLKMLDTDVITDYV 231
            |.|  ..|...:|:||.|.: ||  .:.||...:.||:
Mosquito   195 LKEGFEGQMNADNIEVGICDANG--FRRLDPSDVQDYL 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	PRK03996	5..231	CDD:235192	85/228 (37%)
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	79/209 (38%)
AgaP_AGAP001995	XP_550819.1	proteasome_alpha_type_2	6..231	CDD:239719	86/230 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920