DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4 and AgaP_AGAP003935

DIOPT Version :9

Sequence 1:	NP_525092.1	Gene:	Prosalpha4 / 32584	FlyBaseID:	FBgn0004066	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	XP_318387.2	Gene:	AgaP_AGAP003935 / 1278761	VectorBaseID:	AGAP003935	Length:	246	Species:	Anopheles gambiae

Alignment Length:	241	Identity:	70/241 - (29%)
Similarity:	124/241 - (51%)	Gaps:	5/241 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SSRYDRAVTIFSPDGHLLQVEYAQEAV-RKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVRKIC 65
            |:.:||.:|||||:|.|.|||||.:|: ::|.|::.::|.:|.|:..:||...:|.:...|..:.
Mosquito     6 SAGFDRHITIFSPEGRLYQVEYAFKAINQEGLTSIALKGKDCAVVATQKKIPDKLIDPATVTHLY 70

  Fly    66 MLDNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRPFG 130
            .:...:.....|..||:|..:.||:.|..:.|......:.::.:.|.:|.:.|.|||:...||.|
Mosquito    71 RITREIGCVMTGRIADSRSQVQRARYEAANWRYKYGYEIPVDVLCRRMADISQVYTQNAEMRPLG 135

  Fly   131 ISCLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVANEHGAVKLAIR 195
            .|.::..|||:....:::|:|:|.:..|.|.:.|........:.||..:.:...:|...::|||.
Mosquito   136 CSIVMIAFDAENGPAVYKTDPAGYYCGYHAISVGVKQTEANSYLEKKLKRKAELSEEETIQLAIT 200

  Fly   196 ALLEV--AQSGQNNLEVAIMENGKP-LKMLDTDVITDYV-KIIEKE 237
            .|..|  .......:|:.|:...|| .:.|..|.|..:: .|.||:
Mosquito   201 CLSTVLAVDFKPTEIEIGIVSKEKPEFRTLTEDEIEVHLTAIAEKD 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	PRK03996	5..231	CDD:235192	66/229 (29%)
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	60/210 (29%)
AgaP_AGAP003935	XP_318387.2	PRE1	7..245	CDD:223711	67/237 (28%)
AgaP_AGAP003935	XP_318387.2	proteasome_alpha_type_6	8..220	CDD:239723	60/211 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820