Protein Alignment Prosalpha4 and Prosbeta6

DIOPT Version :10

• Sequence 1: NP_525092.1
• Gene: Prosalpha4 / 32584
• FlyBaseID: FBgn0004066
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: XP_315096.4
• Gene: Prosbeta6 / 1275817
• VectorBaseID: AGAMI1_007544
• Length: 231
• Species: Anopheles gambiae
• Alignment Length: 264
• Identity: 53/264 - (20%)
• Similarity: 89/264 - (33%)
• Gaps: 81/264 - (30%)

  Fly    22 EYAQEAVRK---------GSTAVGVRGANCVVLGVEKK-SVAQLQEDRKVRKICMLDNHVVMAFA 76
            ||.....||         |.:.|.:.|.:..|:|.:.: |.......|...|:..|.:..|:|..
Mosquito     9 EYEVPGARKVQFYPYESNGGSVVAIAGEDFAVIGADTRLSSGYSIHTRTQNKLFRLSDKTVLAST 73

  Fly    77 GLTADARIMINRAQVECQ----SHRLNVEDPVT------LEYITRFIAQLKQKYTQSNGRRPFGI 131
            |...|...:.:..:|..|    .|:.|:..|..      |.|..||.              |:.:
Mosquito    74 GCWCDTLALTSLVKVRMQMYKDQHQKNMSTPAVAQMLSILMYNRRFF--------------PYYV 124

  Fly   132 SCLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVANEHGAVKLAIRA 196
            |.::.|.|.||...::..:|.|........|.|.:..:::...:.
Mosquito   125 SNVLAGLDQDGKGVVYSYDPIGHCEMTTYRAGGSAGPLLQPVLDN-------------------- 169

  Fly   197 LLEVAQSGQNNLEVAIMENGKPLKM--------------LDTDVITD---YVKIIEKE--KEEEL 242
                 |.||.|:   :..:.:|:||              .:.|:.|.   .:.||.|:  |||.|
Mosquito   170 -----QIGQKNM---LNADPEPVKMEKAISIIKDTFISATERDIYTGDSVIINIITKDGIKEETL 226

  Fly   243 EKKK 246
            ..:|
Mosquito   227 HLRK 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	40/210 (19%)
Prosbeta6	XP_315096.4	proteasome_beta_type_1	20..231	CDD:239726	49/253 (19%)