Protein Alignment Prosalpha4 and Prosalpha3

DIOPT Version :10

• Sequence 1: NP_525092.1
• Gene: Prosalpha4 / 32584
• FlyBaseID: FBgn0004066
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: XP_315057.4
• Gene: Prosalpha3 / 1275771
• VectorBaseID: AGAMI1_013809
• Length: 259
• Species: Anopheles gambiae
• Alignment Length: 256
• Identity: 79/256 - (30%)
• Similarity: 141/256 - (55%)
• Gaps: 10/256 - (3%)

  Fly     1 MSSRYDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKV--RK 63
            |:.|||...|||||:|.|.|||||.||:....|::|:...:.::|..|:::..:|. |..:  .|
Mosquito     1 MARRYDSRTTIFSPEGRLYQVEYAMEAISHAGTSLGILAKDGILLAAERRNTNKLL-DNVIFSEK 64

  Fly    64 ICMLDNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRP 128
            |..|::.:|.:.||:|:||.::.|..:|..|.::||..:.:..|.:...:..:||.|||..|:||
Mosquito    65 IYKLNDDMVCSVAGITSDANVLTNLLRVIAQRYQLNYGEAMPCEQLVSHLCDVKQAYTQYGGKRP 129

  Fly   129 FGISCLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVANEHGAVKLA 193
            ||:|.|..|:|......|:|::|||.:..:||...|.::.......::...:.:::... |..||
Mosquito   130 FGVSILYMGWDKHYGYQLYQSDPSGNYGGWKATCIGNNSAAAVSALKQELSDSDISLVQ-AQDLA 193

  Fly   194 IRAL---LEVAQSGQNNLEVAIM--ENGKP-LKMLDTDVITDYVKIIEKEKEEELEKKKQK 248
            ::.|   |::.:.....:|:|::  ||.|. :|:|.:..:...:...||.:.|....||:|
Mosquito   194 VKVLSKTLDMTKLTSEKIEMAVLTRENNKTVIKILSSAEVDGLIAKYEKAEAEAEAAKKEK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	66/212 (31%)
Prosalpha3	XP_315057.4	proteasome_alpha_type_4	3..216	CDD:239721	67/214 (31%)