DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4 and AgaP_AGAP008816

DIOPT Version :9

Sequence 1:	NP_525092.1	Gene:	Prosalpha4 / 32584	FlyBaseID:	FBgn0004066	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	XP_314945.1	Gene:	AgaP_AGAP008816 / 1275676	VectorBaseID:	AGAP008816	Length:	242	Species:	Anopheles gambiae

Alignment Length:	236	Identity:	77/236 - (32%)
Similarity:	132/236 - (55%)	Gaps:	10/236 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SRYDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVRKICML 67
            |.|||.|..|||:|.|.|||||.||::.||||:|:...:.||:.|||:..:.|.|..|:.||..:
Mosquito     6 SEYDRGVNTFSPEGRLFQVEYAIEAIKFGSTAIGISTPDGVVMAVEKRITSSLIEPSKMEKIVEV 70

  Fly    68 DNHVVMAFAGLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKY-----TQSNGRR 127
            |.|:..|.:||.||:|.:::||::|||:|.....:.:::|...:.::.:..::     |.|...|
Mosquito    71 DRHIGCATSGLMADSRTLLDRARIECQNHWFVYNERMSVESCAQAVSNVAIQFGDGDDTDSAMSR 135

  Fly   128 PFGISCLIGGFDADGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSYREEEVANEHGAVKL 192
            |||::.|..|.: :|...|:..:|||.:..:.|.|.|..::..::..::.|.......|  |:.|
Mosquito   136 PFGVAILFAGIE-NGEPQLWHMDPSGTYIRFDAKAIGSGSEGAQQNLQEYYLPTMTIKE--AINL 197

  Fly   193 AIRALLEVAQSGQN--NLEVAIMENGKPLKMLDTDVITDYV 231
            |:..|.:|.:...|  |:||..|...:..:|...:.:.:|:
Mosquito   198 ALSTLKQVMEEKLNSTNVEVMTMTPKELFRMFSKEEVEEYI 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4	NP_525092.1	PRK03996	5..231	CDD:235192	75/232 (32%)
Prosalpha4	NP_525092.1	proteasome_alpha_type_7	5..213	CDD:239724	73/214 (34%)
AgaP_AGAP008816	XP_314945.1	PRK03996	8..240	CDD:235192	76/234 (32%)
AgaP_AGAP008816	XP_314945.1	proteasome_alpha_type_5	8..220	CDD:239722	73/214 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820