Protein Alignment Mfe2 and paaZ

DIOPT Version :10

• Sequence 1: NP_573109.1
• Gene: Mfe2 / 32582
• FlyBaseID: FBgn0030731
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_415905.1
• Gene: paaZ / 945954
• ECOCYCID: G6708
• Length: 681
• Species: Escherichia coli
• Alignment Length: 583
• Identity: 115/583 - (19%)
• Similarity: 200/583 - (34%)
• Gaps: 192/583 - (32%)

  Fly   139 PYMKKQNYGRIIMTSSNSGIYGNFGQVNYTA----AKMGLIGLANTVAIEGARNNVLCNVIVP-T 198
            |..|:..:....:.:|.||:..:....|:..    .|:....|....||           |.| |
E. coli   131 PLSKEGGFAARHLLTSKSGVAVHINAFNFPCWGMLEKLAPTWLGGMPAI-----------IKPAT 184

  Fly   199 AASRMTEGILPDILFNELKPKLIAPVVAYLC--------HESCEDNGSYIESAAGWATKLHMVRG 255
            |.:::|:.::..|:.:.|.|:   ..::.:|        |...:|..::..|||..    .|:|.
E. coli   185 ATAQLTQAMVKSIVDSGLVPE---GAISLICGSAGDLLDHLDSQDVVTFTGSAATG----QMLRV 242

  Fly   256 KGAVLRPSLDDPVTIE----------------------YVKDVWSNVTDMSKAKHLG-------- 290
            :..::..|:  |.|:|                      ::::|...:|..:..|...
E. coli   243 QPNIVAKSI--PFTMEADSLNCCVLGEDVTPDQPEFALFIREVVREMTTKAGQKCTAIRRIIVPQ 305

  Fly   291 AIAEA-SGTLLEVLEKLKEGGGDAIEDAFEFNS----------KELITYALGIGASVKNAKDMRF 344
            |:..| |..|:..|:|:..  ||..::..:..:          :|.:...|..|..::
E. coli   306 ALVNAVSDALVARLQKVVV--GDPAQEGVKMGALVNAEQRADVQEKVNILLAAGCEIR------- 361

  Fly   345 LYENDADFAAIPTFFVLPGLLLQMSTDKLLSKALPNSQVDFSNILHG-EQYLEIVDDLPT----- 403
             ....||.:|...||  |..||..            .|.|.:..:|. |.:..:...:|.
E. coli   362 -LGGQADLSAAGAFF--PPTLLYC------------PQPDETPAVHATEAFGPVATLMPAQNQRH 411

  Fly   404 ------------SGTLLTN----GKVFDVMD--KGSGAVVVTNSESFDES---GRLLVRNQSTTF 447
                        :|||:|.    .:.| :.|  :..|.:.:.|.||..||   |..|.:
E. coli   412 ALQLACAGGGSLAGTLVTADPQIARQF-IADAARTHGRIQILNEESAKESTGHGSPLPQ------ 469

  Fly   448 IV--GAGKFGGKKDPIAGV---------VPLQPAPNRQPDATVQYT----TSEDQAALYR----- 492
            :|  |.|:.||.:: :.|:         ..:|.:|......:.|:.    ..||:...:|
E. coli   470 LVHGGPGRAGGGEE-LGGLRAVKHYMQRTAVQGSPTMLAAISKQWVRGAKVEEDRIHPFRKYFEE 533

  Fly   493 ------------------------LSGDKNPLHIDPQMALLAGFKTPILHGLCTLGFSVRAVLAQ 533
                                    ||||....|:|...|..:.|...::||.    |.:.|....
E. coli   534 LQPGDSLLTPRRTMTEADIVNFACLSGDHFYAHMDKIAAAESIFGERVVHGY----FVLSAAAGL 594

  Fly   534 FADN--NPAL--FKAVKVRFSGPVIPGQTLRV-------DLWKQGTRINFRTVVVETGKEVIS 585
            |.|.  .|.:  :....:||..||.||.|::|       .|.||.:.....|.|||...||.:
E. coli   595 FVDAGVGPVIANYGLESLRFIEPVKPGDTIQVRLTCKRKTLKKQRSAEEKPTGVVEWAVEVFN 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mfe2	NP_573109.1	hydroxyacyl-CoA-like_DH_SDR_c-like	8..257	CDD:187611	26/130 (20%)
		PLN02864	315..598	CDD:178455	74/363 (20%)
paaZ	NP_415905.1	PaaN-DH	4..674	CDD:131331	115/583 (20%)