Protein Alignment Mfe2 and Hsdl2

DIOPT Version :10

• Sequence 1: NP_573109.1
• Gene: Mfe2 / 32582
• FlyBaseID: FBgn0030731
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_077217.2
• Gene: Hsdl2 / 72479
• MGIID: 1919729
• Length: 490
• Species: Mus musculus
• Alignment Length: 251
• Identity: 71/251 - (28%)
• Similarity: 113/251 - (45%)
• Gaps: 47/251 - (18%)

  Fly     1 MSSSDGKLRYDGRVAVVTGAGAGLGREYALLFAERGAKVVV---------NDLGGTHSGDGASQR 56
            |..:.|||.  |....:|||..|:|:..||..|:.||.:|:         ..||..::
Mouse     1 MLPNTGKLA--GCTVFITGASRGIGKAIALKAAKDGANIVIAAKTTQKHPKLLGTIYT------- 56

  Fly    57 AADIVVDEIRKAGGEAVADYNSVIDGAKV---IETAIKAFGRVDILVNNAGILRDRSLVKTSEQD 118
                ..:||..|||.|:.....|.|..::   :|.|::.||.:|||||||..:...:.:.|..:.
Mouse    57 ----AAEEIEAAGGTALPCVVDVRDEQQINSAVEKAVEKFGGIDILVNNASAISLTNTLDTPTKR 117

  Fly   119 WNLVNDVHLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGN---FGQ-VNYTAAKMGL----I 175
            .:|:.:|:.:|::..::|..|::||...|.|:..|....:  |   |.| ..||.||.|:    :
Mouse   118 VDLMMNVNTRGTYLTSKACIPFLKKSKVGHILNLSPPLNL--NPLWFKQHCAYTIAKYGMSMCVL 180

  Fly   176 GLANTVAIEGARNNVLCNVIVPTAASRMTEG-----------ILPDILFNELK-PK 219
            |:|.....|.|.|.:.....:.|||..|..|           |:.|..::..| ||
Mouse   181 GMAEEFRGEIAVNALWPRTAIHTAAMDMLGGSGVENQCRKVDIIADAAYSIFKRPK 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mfe2	NP_573109.1	hydroxyacyl-CoA-like_DH_SDR_c-like	8..257	CDD:187611	68/244 (28%)
		PLN02864	315..598	CDD:178455
Hsdl2	NP_077217.2	HSDL2_SDR_c	8..248	CDD:187663	68/244 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	282..370
		SCP2	390..483	CDD:460423