Protein Alignment Mfe2 and Hsdl2

DIOPT Version :10

• Sequence 1: NP_573109.1
• Gene: Mfe2 / 32582
• FlyBaseID: FBgn0030731
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_651578.1
• Gene: Hsdl2 / 43325
• FlyBaseID: FBgn0039537
• Length: 412
• Species: Drosophila melanogaster
• Alignment Length: 499
• Identity: 128/499 - (25%)
• Similarity: 194/499 - (38%)
• Gaps: 158/499 - (31%)

  Fly     6 GKLRYDGRVAVVTGAGAGLGREYALLFAERGAKVVV--------NDLGGT-HSGDGASQRAADIV 61
            |||.  ||...:|||..|:|:|.||..|..||.:||        ..|.|| :|           .
  Fly     5 GKLA--GRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYS-----------A 56

  Fly    62 VDEIRKAGGEAVADYNSVID------GAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQD-- 118
            .:||.||||:|   |..|:|      ....:|.|:..||.:||::|||..:   ||..|.:.|
  Fly    57 AEEIEKAGGKA---YPCVVDVRDEQQVRSAVEAAVAKFGGIDIVINNASAI---SLTNTPDTDMK 115

  Fly   119 -WNLVNDVHLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGN-FG-QVNYTAAKMGL----IG 176
             ::|:::::.:|:|..::...||:||.|:..|:..|....:... || .|.||.||.|:    :|
  Fly   116 RYDLMHNINTRGTFLVSKVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLG 180

  Fly   177 LANTVAIEGARNNVLC-NVIVPTAASRMTEGILPDILFNELKPKLIAPVV-AYLCHESCEDNGSY 239
            :|.....||...|.|. ...:.|||..|..|  ||......||:::|... |.|..|..:..|.:
  Fly   181 MAAEFKDEGISVNALWPRTAIHTAAIEMLTG--PDSAKWSRKPEIMADAAYAILTREPRQSTGQF 243

  Fly   240 IESAAGWATKLHMVRGKGAVLRPSLDDPVTIEYVKDVWSNVTDMSKAKHLGAIAEASGTLLEVLE 304
            .                       :||                                  ||||
  Fly   244 F-----------------------VDD----------------------------------EVLE 251

  Fly   305 KLKEGGGDAIEDA-FEFNSKELIT--YALGIGASVKNAKDMRFLYENDADFAAIPT--------- 357
              ..|..|..|.| |..|:.:|:.  :....||.|:|        |..|:.||.|.
  Fly   252 --SAGITDLTEYACFRENADKLMVDFFVEEKGAPVEN--------EAAAEDAAAPASGGDVKIPQ 306

  Fly   358 -FFVLPGLLLQMSTDKLLSKALPNSQVDFSNILHGEQYLEIVDDLPTSGTLLTNGKVFDVMDKGS 421
             |..:..||    :.:::||.....|.:.|....|..:|::.:.   ||:.            |:
  Fly   307 LFRKIESLL----SPEIVSKTQAVFQFNISGAEQGTWFLDLKNG---SGSC------------GA 352

  Fly   422 G-------AVVVTNSESFDE--SGRLLVRNQSTTFIVGAGKFGG 456
            |       |.:..||::|.:  ||:|   ..:..::.|..|..|
  Fly   353 GTPTAAPDATLTMNSKNFFDMFSGKL---KAAPAYMTGKLKISG 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mfe2	NP_573109.1	hydroxyacyl-CoA-like_DH_SDR_c-like	8..257	CDD:187611	81/274 (30%)
		PLN02864	315..598	CDD:178455	37/164 (23%)
Hsdl2	NP_651578.1	PRK08278	7..277	CDD:181349	94/349 (27%)
		SCP2	306..408	CDD:442486	23/110 (21%)