DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mfe2 and CG13833

DIOPT Version :9

Sequence 1:	NP_001285318.1	Gene:	Mfe2 / 32582	FlyBaseID:	FBgn0030731	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_651111.1	Gene:	CG13833 / 42718	FlyBaseID:	FBgn0039040	Length:	321	Species:	Drosophila melanogaster

Alignment Length:	264	Identity:	71/264 - (26%)
Similarity:	118/264 - (44%)	Gaps:	41/264 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 GRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGGEA---- 72
            |.||||||||.||||..:|..|::|..:.|.|:..:.:.|...|      :.:|.|...:|
  Fly    52 GEVAVVTGAGHGLGRAISLELAKKGCHIAVVDINVSGAEDTVKQ------IQDIYKVRAKAYKAN 110

  Fly    73 VADYNSVID-GAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHLKGSFKCTQA 136
            |.:|:.::: .:||:|    ..|.|.:||||||::..|::......|..|:.:|:|...|.....
  Fly   111 VTNYDDLVELNSKVVE----EMGPVTVLVNNAGVMMHRNMFNPDPADVQLMINVNLTSHFWTKLV 171

  Fly   137 AFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIE---GARNNVLCNVIVPT 198
            ..|.||:...|.|:..||.:|::.......||..|.|.:....|:.:|   ..:.::....::|:
  Fly   172 FLPKMKELRKGFIVTISSLAGVFPLPYSATYTTTKSGALAHMRTLRMELDLENQKDIHVTTVLPS 236

  Fly   199 ---AASRMTEGILPDILFNELKPKLIAPVVAYLCHESCEDNGSYIESAAGWATKLHMVRGKGAVL 260
               ..|.:|: :...|.|.::.|......||.             ...||      ||||:..:.
  Fly   237 FLRTNSDVTQ-LTHTIGFGDVYPLFTGEEVAQ-------------RIVAG------MVRGEAEIT 281

  Fly   261 RPSL 264
            .|.:
  Fly   282 VPGM 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mfe2	NP_001285318.1	hydroxyacyl-CoA-like_DH_SDR_c-like	8..257	CDD:187611	70/255 (27%)
		PRK07791	11..248	CDD:236099	66/246 (27%)
		PLN02864	315..598	CDD:178455
		hot_dog	<383..442	CDD:294345
		HDE_HSD	471..592	CDD:239532
CG13833	NP_651111.1	adh_short	53..241	CDD:278532	56/197 (28%)
CG13833	NP_651111.1	NADB_Rossmann	54..297	CDD:304358	70/262 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447553
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840