DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mfe2 and CG8888

DIOPT Version :9

Sequence 1:	NP_001285318.1	Gene:	Mfe2 / 32582	FlyBaseID:	FBgn0030731	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_610724.1	Gene:	CG8888 / 36293	FlyBaseID:	FBgn0033679	Length:	388	Species:	Drosophila melanogaster

Alignment Length:	184	Identity:	34/184 - (18%)
Similarity:	71/184 - (38%)	Gaps:	74/184 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KLRYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGGE 71
            |:...|:..::||..|.|    |...|::     ::|||.|
  Fly    90 KVSASGKGVLITGCEAPL----AWYLAKK-----LDDLGFT------------------------ 121

  Fly    72 AVADYNSVI---DGAKVIETAIKAFGRVDILVNNAGILRDRSLVKT-----------SEQDWNLV 122
            ..|.:|:.|   |.||:::....  ||:.:|  :..:..::::::.           :|..|::|
  Fly   122 VYAGFNTPIEESDEAKILKEVTS--GRMKLL--HLDVTSEKTILEAARYVSQHLPHGAEGLWSVV 182

  Fly   123 N----------------------DVHLKGSFKCTQAAFPYMKKQNYGRIIMTSS 154
            :                      |::|.||.:.||...|.:::. :||::..:|
  Fly   183 HCAHWIALGELEWIPFAVLRKSLDLNLLGSARLTQIFLPLVRRA-HGRVVFLTS 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mfe2	NP_001285318.1	hydroxyacyl-CoA-like_DH_SDR_c-like	8..257	CDD:187611	33/183 (18%)
		PRK07791	11..248	CDD:236099	33/180 (18%)
		PLN02864	315..598	CDD:178455
		hot_dog	<383..442	CDD:294345
		HDE_HSD	471..592	CDD:239532
CG8888	NP_610724.1	NADB_Rossmann	96..380	CDD:304358	32/178 (18%)
CG8888	NP_610724.1	adh_short	96..293	CDD:278532	32/178 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447595
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930