DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mfe2 and CG31809

DIOPT Version :9

Sequence 1:	NP_001285318.1	Gene:	Mfe2 / 32582	FlyBaseID:	FBgn0030731	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_001097168.1	Gene:	CG31809 / 318954	FlyBaseID:	FBgn0051809	Length:	316	Species:	Drosophila melanogaster

Alignment Length:	200	Identity:	54/200 - (27%)
Similarity:	86/200 - (43%)	Gaps:	33/200 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 GRVAVVTGAGAGLGREYALLFAERGAKVVV------------NDLGGTHSGDGASQRAADIVVDE 64
            |..||||||..|:|:|||...|.:|..:|:            |::|..:     :.:...||.|.
  Fly    48 GNWAVVTGATDGIGKEYARELARQGLNLVLVSRKEEKLIAVTNEIGSQY-----NVKIKWIVADF 107

  Fly    65 IRKAGGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRD-RSLVKTSEQD-WNLVNDVHL 127
            .:  |.|..|.....::|.:           |.|||||.|.:.| .||.|.||.. |:|:. |::
  Fly   108 AK--GREVYAHIEKELNGIE-----------VGILVNNVGTIHDPESLDKVSEDMLWDLLT-VNV 158

  Fly   128 KGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGARNNVLC 192
            ......|:...|.|..:..|.|:...|:|.:..:.....|.|.|..:......:..|.|.:|:..
  Fly   159 GSVTMLTRKILPQMISRRKGAIVNLGSSSELQPHPNLTAYAATKKFVTHFTKGLEYEVAEHNIHV 223

  Fly   193 NVIVP 197
            .:::|
  Fly   224 QLVMP 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mfe2	NP_001285318.1	hydroxyacyl-CoA-like_DH_SDR_c-like	8..257	CDD:187611	53/199 (27%)
		PRK07791	11..248	CDD:236099	53/199 (27%)
		PLN02864	315..598	CDD:178455
		hot_dog	<383..442	CDD:294345
		HDE_HSD	471..592	CDD:239532
CG31809	NP_001097168.1	17beta-HSD1_like_SDR_c	48..286	CDD:187614	53/199 (27%)
CG31809	NP_001097168.1	DltE	50..302	CDD:223377	52/197 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447666
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930