DRSC/TRiP Functional Genomics Resources

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Protein Alignment kat80 and YNL035C

DIOPT Version :9

Sequence 1:NP_523363.2 Gene:kat80 / 32581 FlyBaseID:FBgn0040207 Length:819 Species:Drosophila melanogaster
Sequence 2:NP_014363.1 Gene:YNL035C / 855695 SGDID:S000004980 Length:389 Species:Saccharomyces cerevisiae


Alignment Length:448 Identity:91/448 - (20%)
Similarity:167/448 - (37%) Gaps:133/448 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    65 CVRF--AYKDNFVYSADDIGIIRRWDLNS----QKIYS--TLNGHMKSVRTLDFNPSGEYVVSGS 121
            |::.  :||...:....: |.||..|.::    |||.:  |....||.:.: ||  |..::||.:
Yeast    18 CLKLQPSYKHGLLTGLSN-GEIRLLDWSTGKSVQKIKASETAINDMKVIGS-DF--SAGHLVSSA 78

  Fly   122 NDTTVRLWDVQNENNCIKVCRGHMSHVNSVKFSPD---GLWIASA---GLEGSILIWDIRKSKQI 180
            :...|:::|::..:...::    .:..||...|.|   ||.....   |::.::.|:||||....
Yeast    79 SIDAVKVFDIRTNDRIAQI----QNEANSPFISLDSRHGLLACGTELQGIDAAVYIYDIRKWDTP 139

  Fly   181 MEFIADPPVTAITCVQFHPFEF-LLAAGRVDGTVSIYDL---EHQQLVSQTTHFYGQAIRCITFS 241
            :..:.|.....:||::|||.:. :|.:|..||..:||||   |.:..:.|..::           
Yeast   140 LRSLIDSHHDDVTCIKFHPSDVNILLSGSTDGYTNIYDLKQDEEEDALHQVINY----------- 193

  Fly   242 DNGECLFVGSSSGISVIGW-EPDR--ELDHIKSTWSSLADMKVVNNKLICGCHEIDTVS------ 297
                       :.|...|| .|.|  .|.|:::                ...||::..|      
Yeast   194 -----------ASIHSCGWLSPKRIFTLSHMET----------------FAIHELNDKSDELKEP 231

  Fly   298 -------INTI-SLDRVIPFYQPPNSLPNFKHNSTNRKSFTRGNQKFRLSVGGAKPAQVQEEHEG 354
                   :..| :.|.|:..|  |..:...|         |:.|      .|.......::|...
Yeast   232 QPLDFGDVREIWNCDYVVDIY--PGLIATGK---------TQEN------CGELCLLPFKDEKVD 279

  Fly   355 DKSGLSSPN-YSLEVVNEAVLESAETSPMSSLPPVHLASMAGSSADLAPHHVVYGGAIDSAL--- 415
            .::|:..|: :..|||.:..           :|..|             .:::|....|..:   
Yeast   280 TENGIVIPHAHGDEVVRDIF-----------IPAQH-------------SNMLYSCGEDGCVKIW 320

  Fly   416 --RQGKYSRVPDNMASYGSSYGAI--DTRLMSLN--EPSSLHKPDIYNLYPLDKNEEA 467
              :||... :|:|...|......:  |.|..|:|  ||..:.|..:......:|:::|
Yeast   321 ENKQGPLD-IPENFWDYSKKMNVLGDDDREGSINLDEPLIIQKESVSTRPRKEKHKKA 377

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kat80NP_523363.2 Katanin_con80 667..803 CDD:290636
WD40 <4..330 CDD:225201 64/299 (21%)
WD40 14..260 CDD:238121 49/212 (23%)
WD40 repeat 22..58 CDD:293791
WD40 repeat 63..99 CDD:293791 11/41 (27%)
WD40 repeat 106..142 CDD:293791 7/35 (20%)
WD40 repeat 148..184 CDD:293791 12/41 (29%)
WD40 repeat 192..228 CDD:293791 15/39 (38%)
WD40 repeat 285..310 CDD:293791 6/38 (16%)
YNL035CNP_014363.1 WD40 <17..212 CDD:421866 54/223 (24%)
WD40 repeat 59..98 CDD:293791 9/45 (20%)
WD40 repeat 106..144 CDD:293791 10/37 (27%)
WD40 140..>325 CDD:421866 45/263 (17%)
WD40 repeat 151..183 CDD:293791 13/31 (42%)
WD40 repeat 242..282 CDD:293791 10/56 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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