DRSC/TRiP Functional Genomics Resources

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Protein Alignment kat80 and ELP2

DIOPT Version :9

Sequence 1:NP_523363.2 Gene:kat80 / 32581 FlyBaseID:FBgn0040207 Length:819 Species:Drosophila melanogaster
Sequence 2:NP_011716.3 Gene:ELP2 / 853114 SGDID:S000003432 Length:788 Species:Saccharomyces cerevisiae


Alignment Length:384 Identity:70/384 - (18%)
Similarity:126/384 - (32%) Gaps:131/384 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 ISKIYDIKAHDSRVTSLDLGETGRVLVTGGEDRNVNLW-AIGQNE--CFMSLTGHNRSIDCVRFA 69
            :|.|:.:|.                :|..|..:.:.|| .|..|.  .:.:|.||...:.||||.
Yeast    20 VSDIHKVKK----------------IVAFGAGKTIALWDPIEPNNKGVYATLKGHEAEVTCVRFV 68

  Fly    70 YKDNFVYSADDIGIIRRW---DLNSQKIYSTLNGHMKSVRTLDFNPSGEYVVSGSNDTTVRLW-- 129
            ...:|:.||.:...::.|   |.:..:...|:..:.|::..|...||  .:..|..|.|:.:|  
Yeast    69 PDSDFMVSASEDHHVKIWKFTDYSHLQCIQTIQHYSKTIVALSALPS--LISVGCADGTISIWRQ 131

  Fly   130 DVQNE-------------------------------------------------NNCIKVCR--- 142
            ::||:                                                 ::.|:.||   
Yeast   132 NIQNDEFGLAHEFTIKKGFFYPLCLSLSKVEEKKYLLAIGGTNVNVFIASFILSDSGIEKCRVVA 196

  Fly   143 ---GHMSHVNSVKF----SPDGLWIASAGLEGSILIWDIR----------KSKQI-------MEF 183
               ||...|.|:.|    :|....:.|...:..|.:|.||          .||::       .:|
Yeast   197 ELEGHEDWVKSLAFRHQETPGDYLLCSGSQDRYIRLWRIRINDLIDDSEEDSKKLTLLSNKQYKF 261

  Fly   184 IADPPVTA--------------ITCVQFHPFEFLLAAGRVDGTVSIYDLEHQQLVSQTTHFYGQA 234
            ..|..:..              |:.:|:|.....|.|...|.::.:::.:      :|:..:..:
Yeast   262 QIDDELRVGINFEALIMGHDDWISSLQWHESRLQLLAATADTSLMVWEPD------ETSGIWVCS 320

  Fly   235 IRCITFSDNGECLFVGSSSGISVIGWEPDRELDHI-----KSTWSSLADMKVVNNKLIC 288
            :|....|..|.....|||.|.....|.....:|..     ..:|.    |....:.:||
Yeast   321 LRLGEMSSKGASTATGSSGGFWSCLWFTHERMDFFLTNGKTGSWR----MWATKDNIIC 375

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kat80NP_523363.2 Katanin_con80 667..803 CDD:290636
WD40 <4..330 CDD:225201 70/384 (18%)
WD40 14..260 CDD:238121 62/343 (18%)
WD40 repeat 22..58 CDD:293791 7/38 (18%)
WD40 repeat 63..99 CDD:293791 10/38 (26%)
WD40 repeat 106..142 CDD:293791 10/86 (12%)
WD40 repeat 148..184 CDD:293791 11/56 (20%)
WD40 repeat 192..228 CDD:293791 6/35 (17%)
WD40 repeat 285..310 CDD:293791 2/4 (50%)
ELP2NP_011716.3 WD40 52..413 CDD:238121 61/336 (18%)
WD40 repeat 62..102 CDD:293791 10/39 (26%)
WD40 repeat 108..144 CDD:293791 9/37 (24%)
WD40 repeat 153..199 CDD:293791 3/45 (7%)
WD40 repeat 206..264 CDD:293791 11/57 (19%)
WD40 repeat 284..322 CDD:293791 7/43 (16%)
WD40 repeat 341..382 CDD:293791 6/39 (15%)
WD40 repeat 388..412 CDD:293791
WD40 repeat 443..534 CDD:293791
WD40 554..>786 CDD:421866
WD40 repeat 561..604 CDD:293791
WD40 repeat 610..651 CDD:293791
WD40 repeat 656..698 CDD:293791
WD40 repeat 705..746 CDD:293791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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